Protein Alignment HOXA10 and Rx

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 105/501 - (20%)
• Similarity: 157/501 - (31%)
• Gaps: 191/501 - (38%)

Human     3 ARKGYLLP-SPNYPTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLP 66
            |:.|..|| .|..|        |......|.:......|:..||..|.....|.|:..|.|
  Fly   213 AKNGGALPYGPPTP--------PGGQQPQVPNATPLHHGQQMGGQAGHATHAGHGHPTHHG---- 265

Human    67 PAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDL---WLDAPRSCRME 128
               ..|:|..:                      ..|.|.|.|||| .|.:.   :|::... .:|
  Fly   266 ---HAPFGYHN----------------------AFGFGQGGHGYG-HPEEAAGNYLNSMHQ-MVE 303

Human   129 PPDGPPPPPQQQPPPPPQPPQ---PAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAP 190
            ............|||.|.||.   ...|..:...||..::::.:..|             |:.:|
  Fly   304 ANQLQTGANGANPPPAPLPPSSFGSHQQHLAALAAQAQEQQNQHSKY-------------AKSSP 355

Human   191 FPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPA 255
            ...||||           |...||..||   ||                  |..|....:| ..:
  Fly   356 TGAGPPP-----------PPGAYFMESQ---TA------------------PVAPSQINYD-ERS 387

Human   256 LASGS------ADAARKERALDSPPPPT----------------------LACG----------- 281
            ::|.|      .|||:.:..:.|||.|:                      ||.|
  Fly   388 MSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIRP 452

Human   282 ----------------------------------------------SGGGSQGD--EEAHASSSA 298
                                                          :|..:.||  |..:|.|.:
  Fly   453 RSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDS 517

Human   299 AEELSPAPSE-----SSKASPEKDSLGN---SKGENAANWLTAKSGRKKRCPYTKHQTLELEKEF 355
            ....|.|.||     :|....||.:.|:   .:.:|.|.    |..|:.|..:|.:|..|||:.|
  Fly   518 LVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAK----KKHRRNRTTFTTYQLHELERAF 578

Human   356 LFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIR 401
            ..:.|.....|.|::..|:|.:.:|::||||||.|.::..:...:|
  Fly   579 EKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLR 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		17/74 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		35/212 (17%)
		Homeobox	339..392	CDD:278475	20/52 (38%)
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	20/51 (39%)
		OAR	876..892	CDD:281777

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910