DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXA10 and lms

DIOPT Version :9

Sequence 1:	NP_061824.3	Gene:	HOXA10 / 3206	HGNCID:	5100	Length:	410	Species:	Homo sapiens
Sequence 2:	NP_001286635.1	Gene:	lms / 37322	FlyBaseID:	FBgn0034520	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	118	Identity:	37/118 - (31%)
Similarity:	55/118 - (46%)	Gaps:	19/118 - (16%)

- Green bases have known domain annotations that are detailed below.

Human   281 GSGGGSQGDEEAHA---SSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKK--R 340
            |.||...|...|.:   ||...:.:....|:...||.:.:.||:.              |||  |
  Fly    40 GRGGNCLGASRASSPATSSCLDDNMDDGKSDIDLASDDGNGLGDD--------------RKKRPR 90

Human   341 CPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 393
            ..::..|...||.||....||:..:|..:::.:.||:.|:||||||||.|.|:
  Fly    91 TAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKR 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..158
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..339		13/60 (22%)
		Homeobox	339..392	CDD:278475	22/54 (41%)
lms	NP_001286635.1	Cnd2	33..>106	CDD:303063	20/79 (25%)
lms	NP_001286635.1	Homeobox	89..142	CDD:278475	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910