Protein Alignment HOXA10 and en

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 69/259 - (26%)
• Similarity: 97/259 - (37%)
• Gaps: 41/259 - (15%)

Human   150 PAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYF 214
            |.|.::..|.|.  .|:|:.     ...|..||......||....||....|...:|..|.....
  Fly   279 PPPMSSKMSDAN--PEKSAL-----GSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNAS 336

Human   215 RLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGR-GFDLPPALASGSADAARKERALDSPPPPTL 278
            .:|.....|....|...|... .|....:.|..| |       ||||...|...:....|||..:
  Fly   337 TISSTSSVATSSSSSSSGCSS-AASSLNSSPSSRLG-------ASGSGVNASSPQPQPIPPPSAV 393

Human   279 ACGSGGGSQGDEEAHASSSAAE----ELSPA----------PSESSKASPEKDSLGNSKGENAAN 329
            :..||..|..|..:...|:..|    |:.||          ||...:....|.....:..|
  Fly   394 SRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDE---- 454

Human   330 WLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 393
                   ::.|..::..|...|::||..|.|||..||.::|..:.|.:.|:||||||:|.|:||
  Fly   455 -------KRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		28/132 (21%)
		Homeobox	339..392	CDD:278475	22/52 (42%)
en	NP_523700.2	Homeobox	457..510	CDD:278475	22/52 (42%)
		Engrail_1_C_sig	512..541	CDD:287495	69/259 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910