Protein Alignment HOXA10 and cad

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 124/292 - (42%)
• Gaps: 69/292 - (23%)

Human   150 PAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYF 214
            || .:|:.:|.||:...:...:..........|:::|              :.|:||....||..
  Fly    86 PA-SSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSA--------------SSGSSSSGGAPGAP 135

Human   215 RLSQAYGTAKGYGSGGGGAQQLGA---GPFPAQPP-----GRGFDLPPALASGSADAARKERALD 271
            :|::. .::.|.|..|||....||   ||..|.|.     ..|...||...|||        .:.
  Fly   136 QLNET-NSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGS--------EIS 191

Human   272 SPPPPTLAC-----------------GSGGGSQGDEEAHASSSAAEELS----PAPSE------- 308
            ||..||.|.                 .:...:......|.:::....:|    .:||:
  Fly   192 SPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWM 256

Human   309 ---SSKASPEKDSLGNSKGENAANWLTAKSGR-----KKRCPYTKHQTLELEKEFLFNMYLTRER 365
               :..|.|:.|...:...|:.::.|.| ||:     |.|..||..|.||||||:..:.|:|..|
  Fly   257 KKPAYPAQPQPDLSSSPNLEDLSDLLDA-SGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRR 320

Human   366 RLEISRSVHLTDRQVKIWFQNRRMKLKKMNRE 397
            :.|:::::.|::|||||||||||.|.:|.|::
  Fly   321 KSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		34/161 (21%)
		Homeobox	339..392	CDD:278475	27/52 (52%)
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	27/51 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910