Protein Alignment HOXA10 and Lim3

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 64/357 - (17%)
• Similarity: 96/357 - (26%)
• Gaps: 139/357 - (38%)

Human   133 PPP-------------PPQQQPPPPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSAT 184
            |||             ||||||.|..|...|..|....|...|.::..           |.:...
  Fly     8 PPPLHHHHQHQHQLQHPPQQQPHPHQQLQHPLQQQQHLSAMDNHQQHQ-----------PHIHQQ 61

Human   185 AAELAPFPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGP----FPAQP 245
            ..:....|  |.|....|                           .||.||....|    .....
  Fly    62 QQQQQQLP--PTPQASHL---------------------------VGGQQQQQQHPHHNHLAVDQ 97

Human   246 PGRGFDLPPALASGSADAARKERALDSPPP------------------------PTLACGSGGGS 286
            .....:|..||.|       :.|||::..|                        ..|.|....|.
  Fly    98 DDPNPELVLALIS-------RNRALEATIPKCGGCHELILDRFILKVLERTWHAKCLQCSECHGQ 155

Human   287 QGDE---------------EAHASSSAAEELSPAPS----------------------------- 307
            ..|:               :.:.:..:|.::...|:
  Fly   156 LNDKCFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGD 220

Human   308 -----ESSKASPEKD-SLGNSKGENAANWLTAKSGRKK-RCPYTKHQTLELEKEFLFNMYLTRER 365
                 |..|...::| ....:||......|......|: |...|..|...|:..:..:....|..
  Fly   221 EFYLMEDRKLICKRDYEEAKAKGLYLDGSLDGDQPNKRPRTTITAKQLETLKTAYNNSPKPARHV 285

Human   366 RLEISRSVHLTDRQVKIWFQNRRMKLKKMNRE 397
            |.::|:...|..|.|::||||||.|.|::.::
  Fly   286 REQLSQDTGLDMRVVQVWFQNRRAKEKRLKKD 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		13/37 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		25/195 (13%)
		Homeobox	339..392	CDD:278475	17/53 (32%)
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	4/50 (8%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	4/54 (7%)
		Homeobox	259..312	CDD:278475	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910