Protein Alignment HOXA10 and Gsc

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 445
• Identity: 89/445 - (20%)
• Similarity: 134/445 - (30%)
• Gaps: 176/445 - (39%)

Human    93 SPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQ-----------QPPPPPQ 146
            :||.||||                       :....|...|..||.:           .|.|||.
  Fly     7 TPGGGGGG-----------------------TTTTTPSTTPDIPPSKAKFKITVVSTPSPSPPPT 48

Human   147 PPQPAPQATSCSFAQNIKEES---SYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGV 208
            || ||    ....||.::..|   .|.|..|.....:......:::..|          |.::..
  Fly    49 PP-PA----GSMLAQMVETNSPPAGYTLKRSPSDLGEQQQPPRQISRSP----------GNTAAY 98

Human   209 PVP----------GYF--RL---------------SQAYGTAKGYGSG---------GG------ 231
            .:.          ||.  ||               ||...:..|..||         ||
  Fly    99 HLTTAMLLNSQQCGYLGQRLQSVLQQQHAQHQQSQSQTPSSDDGSQSGVTILEEERRGGAAAASL 163

Human   232 -------GAQQLGAGPFPAQPPGRGFDLPP-----ALASGSADAARKERALDSPPPPTLACGSGG 284
                   |::|.|.|..|:|    |..:..     .|.|.......|....:||..|.....|..
  Fly   164 FTIDSILGSRQQGGGTAPSQ----GSHISSNGNQNGLTSNGISLGLKRSGAESPASPNSNSSSSA 224

Human   285 GSQ--------------GDEEAHASSSAAEELSPAPSE--------------------------- 308
            .:.              |....|.:::||...:.:||:
  Fly   225 AASPIRPQRVPAMLQHPGLHLGHLAAAAASGFAASPSDFLVAYPNFYPNYMHAAAVAHVAAAQMQ 289

Human   309 ---SSKAS---------------PEKDSLG-NSKGENAANWL----TAKSGRKKRCPYTKHQTLE 350
               |..|:               |....|| :..|::..:.|    ..|..|:.|..:|:.|..:
  Fly   290 AHVSGAAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHHLSHLGHGPPPKRKRRHRTIFTEEQLEQ 354

Human   351 LEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRE--NRIREL 403
            ||..|....|.....|.:::..|.|.:.:|::||:|||.|.:|..||  .|:|:|
  Fly   355 LEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERLRKL 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		18/75 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		34/208 (16%)
		Homeobox	339..392	CDD:278475	17/52 (33%)
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910