DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXA10 and al

DIOPT Version :9

Sequence 1:	NP_061824.3	Gene:	HOXA10 / 3206	HGNCID:	5100	Length:	410	Species:	Homo sapiens
Sequence 2:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	44/149 - (29%)
Similarity:	63/149 - (42%)	Gaps:	34/149 - (22%)

- Green bases have known domain annotations that are detailed below.

Human   251 DLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPE 315
            |..|..::.||.||.......|...|:.|.|:.||:.                         ||.
  Fly    28 DRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTN-------------------------SPV 67

Human   316 KDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMY---LTRERRLEISRSVHLTD 377
            .|  |||..| |..:...:..|:.|..:|..|..||||.|....|   .|||   |::..:.||:
  Fly    68 SD--GNSDCE-ADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTRE---ELAMKIGLTE 126

Human   378 RQVKIWFQNRRMKLKKMNR 396
            .::::||||||.|.:|..:
  Fly   127 ARIQVWFQNRRAKWRKQEK 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..158
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..339		21/87 (24%)
		Homeobox	339..392	CDD:278475	22/55 (40%)
al	NP_722629.1	Homeobox	89..141	CDD:278475	22/54 (41%)
al	NP_722629.1	OAR	374..391	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910