Protein Alignment HOXA10 and B-H1

DIOPT Version :9

• Sequence 1: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 401
• Identity: 87/401 - (21%)
• Similarity: 124/401 - (30%)
• Gaps: 131/401 - (32%)

Human    16 TTMSCSESPAANSFLVDSLISSGRGEA---------------GGGGGGAGGGGGGGYYAHGGVYL 65
            ||.|....|..:.|:::.:::.....|               .....|:.||....:..:..
  Fly    64 TTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNN--- 125

Human    66 PPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPP 130
                             .:.|...||    |...|.|:.|.|. :.|.|             .||
  Fly   126 -----------------NINGDNCEA----SNVAGVGVLPSAL-HHPQP-------------HPP 155

Human   131 DGPPPPPQQQPPPPPQ----PPQPAPQATS-CSFAQNIKEESSYCLYDSADKCPKVSATAAELAP 190
            ..|...|.....|..:    ||.......: ..:|..:::..:.....:|.:....:|.||..|.
  Fly   156 THPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAA 220

Human   191 FPRG---PPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDL 252
            ...|   ||.||   |...||            |.|                     ||..| ||
  Fly   221 AAAGVAAPPVDG---GVDGGV------------GLA---------------------PPAGG-DL 248

Human   253 PPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKD 317
                 ..|:|...:....||......:..|.||...|                 ..|.|:....|
  Fly   249 -----DDSSDYHEENEDCDSGNMDDHSVCSNGGKDDD-----------------GNSVKSGSTSD 291

Human   318 SLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKI 382
            ..|.||.:           ||.|..:|.||...|||.|....||:.:.|.|::..:.|:|.|||.
  Fly   292 MSGLSKKQ-----------RKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKT 345

Human   383 WFQNRRMKLKK 393
            |:||||.|.|:
  Fly   346 WYQNRRTKWKR 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		16/73 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		22/117 (19%)
		Homeobox	339..392	CDD:278475	23/52 (44%)
B-H1	NP_523387.1	Homeobox	303..355	CDD:278475	23/51 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910