Protein Alignment Antdh and CBR3

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001227.1
• Gene: CBR3 / 874
• HGNCID: 1549
• Length: 277
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 78/293 - (26%)
• Similarity: 119/293 - (40%)
• Gaps: 76/293 - (25%)

  Fly     6 NRVAVVTGASSGIGSAIAKDLV--LAGMTVVGLARRVDRVKELQRELPAEKRGKLFALYCDVGNE 68
            :|||:||||:.|||.|||::|.  .:| .||..||.|.|.:...::|.||.....|. ..|:.:.
Human     5 SRVALVTGANRGIGLAIARELCRQFSG-DVVLTARDVARGQAAVQQLQAEGLSPRFH-QLDIDDL 67

  Fly    69 SSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVM----QQVLQTNIMGIVLCTQRAVRS 129
            .|:....|::.::.|.::||||||..   .:..| :|...    :..|:||..        |.|:
Human    68 QSIRALRDFLRKEYGGLNVLVNNAAV---AFKSD-DPMPFDIKAEMTLKTNFF--------ATRN 120

  Fly   130 MRER-----KFDGHVVLINSILGHKTM--------------TATEGVAPDV-------------- 161
            |...     |..|.||.|:|:...:..              |.|||...|:
Human   121 MCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185

  Fly   162 ------NVYPPSKHAVTALAE--GYRQEFFGLGTRIKITSVSPGVVDTEI-VPDSIREAIKDRML 217
                  :.|..||..||.|:.  ..|.:......||.:.:..||.|.|:: ..||||..
Human   186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTV------ 244

  Fly   218 HSEDIAQGVLYAIATPPHVQ------VHELIIK 244
              |:.|:..:|....||...      ||:.:::
Human   245 --EEGAETPVYLALLPPDATEPQGQLVHDKVVQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	78/293 (27%)
CBR3	NP_001227.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	78/292 (27%)