Protein Alignment Antdh and CBR1

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001748.1
• Gene: CBR1 / 873
• HGNCID: 1548
• Length: 277
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 69/273 - (25%)
• Similarity: 114/273 - (41%)
• Gaps: 60/273 - (21%)

  Fly     8 VAVVTGASSGIGSAIAKDLV-LAGMTVVGLARRVDRVKELQRELPAEKRGKLFALYCDVGNESSV 71
            ||:|||.:.|||.||.:||. |....||..||.|.|.:...::|.||.....|. ..|:.:..|:
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFH-QLDIDDLQSI 70

  Fly    72 NEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQ--VLQTNIMGI-VLCTQ--------- 124
            ....|::.::.|.:||||||||....  :.|..|..:|.  .::||..|. .:||:
Human    71 RALRDFLRKEYGGLDVLVNNAGIAFK--VADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQG 133

  Fly   125 -----------RAVRSMR---ERKFDGHVVLINSILG--HKTMTATEGVAPDVNVYPPSKHAVT- 172
                       ||::|..   ::||....:....::|  :|.:..|:........:|.|.:.||
Human   134 RVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTK 198

  Fly   173 ------------ALAEGYRQEFFGLGTRIKITSVSPGVVDTEIV-PDSIREAIKDRMLHSEDIAQ 224
                        .|:|..:      |.:|.:.:..||.|.|::. |.:.:.        .|:.|:
Human   199 IGVTVLSRIHARKLSEQRK------GDKILLNACCPGWVRTDMAGPKATKS--------PEEGAE 249

  Fly   225 GVLYAIATPPHVQ 237
            ..:|....||..:
Human   250 TPVYLALLPPDAE 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	69/273 (25%)
CBR1	NP_001748.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	69/273 (25%)