Protein Alignment Antdh and DHRS11

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 93/255 - (36%)
• Similarity: 149/255 - (58%)
• Gaps: 15/255 - (5%)

  Fly     1 MERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQREL-PAEKRGKLFALYCD 64
            ||||::|:|:|||||.|||:|:|:.||..|:.|||.||.|..::||..|. .|...|.|....||
Human     6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 70

  Fly    65 VGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRS 129
            :.||..:...|..|..:...:|:.:||||..:|..|:..:.:..:.:...|::.:.:||:.|.:|
Human    71 LSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQS 135

  Fly   130 MRERKF-DGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTRIKITS 193
            |:||.. |||::.|||:.||:.:..:.     .:.|..:|:|||||.||.|||.....|.|:.|.
Human   136 MKERNVDDGHIININSMSGHRVLPLSV-----THFYSATKYAVTALTEGLRQELREAQTHIRATC 195

  Fly   194 VSPGVVDTEIV-------PDSIREAIKD-RMLHSEDIAQGVLYAIATPPHVQVHELIIKP 245
            :|||||:|:..       |:......:. :.|..||:|:.|:|.::||.|:|:.::.::|
Human   196 ISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	92/253 (36%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	93/255 (36%)