Protein Alignment Antdh and DHRS7

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_057113.1
• Gene: DHRS7 / 51635
• HGNCID: 21524
• Length: 339
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 75/219 - (34%)
• Similarity: 110/219 - (50%)
• Gaps: 25/219 - (11%)

  Fly     4 WQNR---------VAVVTGASSGIGSAIAKDLVLAGMTVVGLARRV---DRVKELQRELPAEKRG 56
            ||.|         |..|||||||||..:|..|...|:::|..||||   :|||....|....|..
Human    39 WQGRRPEWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEK 103

  Fly    57 KLFALYCDVGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVL 121
            .:..|..|:.:..|...|...::|:.|.||:||||.|..|....:|.:..|.:::::.|.:|.|.
Human   104 DILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168

  Fly   122 CTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLG 186
            .|:..:..|.||| .|.:|.:|||||..::..:.|       |..||||:.....|.|.|   |.
Human   169 LTKCVLPHMIERK-QGKIVTVNSILGIISVPLSIG-------YCASKHALRGFFNGLRTE---LA 222

  Fly   187 T--RIKITSVSPGVVDTEIVPDSI 208
            |  .|.::::.||.|.:.||.:|:
Human   223 TYPGIIVSNICPGPVQSNIVENSL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	75/219 (34%)
DHRS7	NP_057113.1	11beta-HSD1_like_SDR_c	48..308	CDD:187593	72/210 (34%)