DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment antdh and Dhrs11

DIOPT Version :9

Sequence 1:	NP_572695.2	Gene:	antdh / 32058	FlyBaseID:	FBgn0026268	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_038942294.1	Gene:	Dhrs11 / 360583	RGDID:	1307935	Length:	299	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	90/249 - (36%)
Similarity:	139/249 - (55%)	Gaps:	34/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQREL-PAEKRGKLFALYCD 64
            ||||::|:|:|||||.|||:|:|:.||..|:.|||.||.|..::||..|. .|...|.|....||
  Rat    76 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 140

  Fly    65 VGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRS 129
            :.||..:...|..:..:...:|:.:||||..:|..|:..:.:..:.:...|::.:.:||:.|.:|
  Rat   141 LSNEEDILSMFSAVRSQHSGVDICINNAGMARPDSLLSGSTSGWKDMFNVNVLALSICTREAYQS 205

  Fly   130 MRERKF-DGHVVLINSILGHKTMTATEGVAPD--VNVYPPSKHAVTALAEGYRQEFFGLGTRIKI 191
            |:||.. |||::.|||:.||:       |.|.  ::.|..:|:|||||.||.|||.....|.|:.
  Rat   206 MKERNVDDGHIININSMCGHR-------VPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRA 263

  Fly   192 TSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHELIIKP 245
            |.:.|                       ||:|:.|:|.::|||||||.::.::|
  Rat   264 TCLRP-----------------------EDVAEAVIYVLSTPPHVQVGDIQMRP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
antdh	NP_572695.2	YdfG	1..250	CDD:226674	90/249 (36%)
antdh	NP_572695.2	NADB_Rossmann	1..245	CDD:304358	89/247 (36%)
Dhrs11	XP_038942294.1	Mgc4172-like_SDR_c	76..295	CDD:187601	90/249 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337095
Domainoid	1	1.000	151	1.000	Domainoid score	I4244
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41560
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3811
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm44892
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770