DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment antdh and dhs-6

DIOPT Version :9

Sequence 1:	NP_572695.2	Gene:	antdh / 32058	FlyBaseID:	FBgn0026268	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001021972.1	Gene:	dhs-6 / 3565470	WormBaseID:	WBGene00000970	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	62/238 - (26%)
Similarity:	104/238 - (43%)	Gaps:	24/238 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQREL--PAEK----RGKLFAL 61
            ::..|..::||||.|||..||..|...|..:|..|:......:|...:  .||:    .||....
Worm     6 KFVGRTVLITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYSAAEEIEKAGGKALPC 70

  Fly    62 YCDVGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQ---VLQTNIMGIVLCT 123
            ..||.:|:||..:.:..::|.|.||:|:|||..:.   |.|.....|::   :...|..|..|.|
Worm    71 IVDVRDEASVKASVEEAVKKFGGIDILINNASAIS---LTDTENTEMKRYDLMHSINTRGTFLMT 132

  Fly   124 QRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTR 188
            :..:..::..| :.||:.|:..|..:|......||     |..:|:.::....|..:||...|..
Worm   133 KTCLPYLKSGK-NPHVLNISPPLLMETRWFANHVA-----YTMAKYGMSMCVLGQHEEFRPHGIA 191

  Fly   189 IK----ITSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVL 227
            :.    :|::....:  |::.|...||...:.....|.|..||
Worm   192 VNALWPLTAIWTAAM--EMLSDKGGEAGSRKPSIMADAAYAVL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
antdh	NP_572695.2	YdfG	1..250	CDD:226674	62/238 (26%)
antdh	NP_572695.2	NADB_Rossmann	1..245	CDD:304358	62/238 (26%)
dhs-6	NP_001021972.1	PRK08278	9..275	CDD:181349	62/235 (26%)
dhs-6	NP_001021972.1	SCP2	319..411	CDD:376720
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930