Protein Alignment Antdh and Dhrs7b

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001008507.1
• Gene: Dhrs7b / 287380
• RGDID: 1311243
• Length: 325
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 74/240 - (30%)
• Similarity: 117/240 - (48%)
• Gaps: 24/240 - (10%)

  Fly     5 QNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQREL--PAEKRGKLF---ALYCD 64
            :|.|.|||||:||:|...|:....||..||...|.|..::|..|||  .:..:|:..   .:..|
  Rat    51 RNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTHQPCVVTFD 115

  Fly    65 VGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRS 129
            :.:..::..|...|:|..|.:|:|:||||....|.:.|....|.::|::.|..|.|..|:..:.|
  Rat   116 LADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFGPVALTKALLPS 180

  Fly   130 MRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTRIKITSV 194
            |.||| .||:|.|:||.|..::       |..:.|..||||..|..:..|.|.  ..:.|::|.:
  Rat   181 MVERK-RGHIVAISSIQGKISI-------PFRSAYAASKHATQAFFDCLRAEM--KDSDIEVTVI 235

  Fly   195 SPGVVDTE-----IVPDSIREAIKDRML----HSEDIAQGVLYAI 230
            |||.:.|.     :..|..|....|:..    .:.::||.:..|:
  Rat   236 SPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAVEVAQDIFDAV 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	74/240 (31%)
Dhrs7b	NP_001008507.1	11beta-HSD1_like_SDR_c	50..311	CDD:187593	74/240 (31%)