DRSC/TRiP Functional Genomics Resources

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Protein Alignment antdh and DHRS7B

DIOPT Version :9

Sequence 1:NP_572695.2 Gene:antdh / 32058 FlyBaseID:FBgn0026268 Length:250 Species:Drosophila melanogaster
Sequence 2:XP_011522088.1 Gene:DHRS7B / 25979 HGNCID:24547 Length:334 Species:Homo sapiens


Alignment Length:209 Identity:69/209 - (33%)
Similarity:109/209 - (52%) Gaps:15/209 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 QNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQRELPAEKRGKL-----FALYCD 64
            :|.|.|:|||:||:|...||....||..:|...|....::||.|||.|....|:     :.:..|
Human    98 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFD 162

  Fly    65 VGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRS 129
            :.:..::..|...|:|..|.:|:||||||....|.::|....|.::|::||..|.|..|:..:.|
Human   163 LTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPS 227

  Fly   130 MRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTRIKITSV 194
            |.:|: .||:|.|:||.|..::       |..:.|..||||..|..:..|.|....  .|::|.:
Human   228 MIKRR-QGHIVAISSIQGKMSI-------PFRSAYAASKHATQAFFDCLRAEMEQY--EIEVTVI 282

  Fly   195 SPGVVDTEIVPDSI 208
            |||.:.|.:..::|
Human   283 SPGYIHTNLSVNAI 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
antdhNP_572695.2 YdfG 1..250 CDD:226674 69/209 (33%)
NADB_Rossmann 1..245 CDD:304358 69/209 (33%)
DHRS7BXP_011522088.1 11beta-HSD1_like_SDR_c 97..>304 CDD:187593 69/209 (33%)
adh_short 101..294 CDD:278532 67/202 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1205
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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