Protein Alignment Antdh and Hsd11b1

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_058776.2
• Gene: Hsd11b1 / 25116
• RGDID: 2834
• Length: 288
• Species: Rattus norvegicus
• Alignment Length: 251
• Identity: 61/251 - (24%)
• Similarity: 102/251 - (40%)
• Gaps: 44/251 - (17%)

  Fly     2 ERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVV-------GLARRVDRVKELQRELPAEKRGKLF 59
            |..|.:..:|||||.|||..:|..|...|..||       ||.:.|.|..||         |...
  Rat    26 EMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLEL---------GAAS 81

  Fly    60 ALYCDVGNESSVNEAFDWIIQK---LGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVL 121
            |.|. .|....:..|..::::.   ||.:|:|:.|..|.....|...:...:::.::.|.:..|:
  Rat    82 AHYI-AGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVV 145

  Fly   122 CTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLG 186
            .:..|:..:::.  :|.:.:|:|:.|..|.       |.:..|..||.|:.......|:|.....
  Rat   146 LSTAALPMLKQS--NGSIAIISSMAGKMTQ-------PLIASYSASKFALDGFFSTIRKEHLMTK 201

  Fly   187 TRIKITSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHELI 242
            ..:.||....|.:|||       .|:|:        ..|::.:.|.|......|:|
  Rat   202 VNVSITLCVLGFIDTE-------TALKE--------TSGIILSQAAPKEECALEII 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	61/251 (24%)
Hsd11b1	NP_058776.2	11beta-HSD1_like_SDR_c	28..275	CDD:187593	60/249 (24%)