Protein Alignment Antdh and Hsd11b1

DIOPT Version :10

• Sequence 1: NP_572695.2
• Gene: Antdh / 32058
• FlyBaseID: FBgn0026268
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_006497291.1
• Gene: Hsd11b1 / 15483
• MGIID: 103562
• Length: 304
• Species: Mus musculus
• Alignment Length: 251
• Identity: 63/251 - (25%)
• Similarity: 105/251 - (41%)
• Gaps: 44/251 - (17%)

  Fly     2 ERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVV-------GLARRVDRVKELQRELPAEKRGKLF 59
            |..|.:..:|||||.|||..:|..|...|..||       ||.:.|.|..||         |...
Mouse    42 EMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLEL---------GAAS 97

  Fly    60 ALYCDVGNESSVNEAFDWIIQK---LGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVL 121
            |.|. .|....:..|..:|::.   :|.:|:|:.|..|.....|...:...:::|::.|.:..|:
Mouse    98 AHYI-AGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVV 161

  Fly   122 CTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLG 186
            .:..|:..:::.  :|.:.:|:|:.|..|.       |.:..|..||.|:.......|.|.:...
Mouse   162 MSTAALPMLKQS--NGSIAVISSLAGKMTQ-------PMIAPYSASKFALDGFFSTIRTELYITK 217

  Fly   187 TRIKITSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHELI 242
            ..:.||....|::|||       .|:|:        ..|::.|.|:|......|:|
Mouse   218 VNVSITLCVLGLIDTE-------TAMKE--------ISGIINAQASPKEECALEII 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antdh	NP_572695.2	Rossmann-fold NAD(P)(+)-binding proteins	1..245	CDD:473865	63/251 (25%)
Hsd11b1	XP_006497291.1	11beta-HSD1_like_SDR_c	44..291	CDD:187593	62/249 (25%)