DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dlic and dync1li1

DIOPT Version :9

Sequence 1:	NP_572694.1	Gene:	Dlic / 32057	FlyBaseID:	FBgn0030276	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001072301.1	Gene:	dync1li1 / 779754	XenbaseID:	XB-GENE-490205	Length:	508	Species:	Xenopus tropicalis

Alignment Length:	491	Identity:	229/491 - (46%)
Similarity:	312/491 - (63%)	Gaps:	33/491 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TNALTSSFTMKKKDAAAEK----ENLWSAILNEVQTQGSTKLPSNKSVLVLGDNATGKTTLIAKL 69
            :::..:.:...:..|.|.:    :||||:||:||.|:..:||||.|:||:||::..|||:||.||
Frog    13 SSSFNAGYGQNQSGATASEDEDGQNLWSSILSEVSTRSRSKLPSGKNVLLLGEDGAGKTSLIGKL 77

  Fly    70 QGVEDPKKGSGLEYAYIDVKDEYRDDMTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSM 134
            ||:|:.|||.|:||.||:|.||.|||.||..||:||||..|..||.:|::.::...||::|.|.|
Frog    78 QGIEEYKKGRGMEYLYINVHDEDRDDQTRCNVWILDGDLYHKGLLKFAMDPSSVRDTLIMLVVDM 142

  Fly   135 TQPWGWLEQLNHWIKVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKRTMRNN 199
            ::||..|:.|..|..|:.:|:|.|::..:|.:...:::...:|.|.|.|::. |.||.|   ||.
Frog   143 SRPWLALDSLQKWASVIREHVDKLKIPPEEMKEMEEKIVRNFQEYVEPGEEF-PASPQK---RNT 203

  Fly   200 SIDEDD---LLPLTEDALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHG 261
            |.||.|   :|||.||.|..|||:.:|||.||.|.::.||||::||||||||||..||.|||::|
Frog   204 SSDEQDDSVILPLGEDTLTHNLGIPVVVVCTKCDAISILEKEHDYRDEHFDFIQSHIRKFCLQYG 268

  Fly   262 TSLFYTSVKEDKNCDVLYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVK 326
            .:|.|||:||:||.|::|||:..::||..|..||:|||||||.||||||:.|||.||:||...:|
Frog   269 AALIYTSIKENKNIDIVYKYIVQQLYGFLFNMPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLK 333

  Fly   327 AENPYTDIIKSPPTRKAVSNREAEVQTEDEQAFLARQQ-EILKQGDQVRGESPLRSQGVGSNKSG 390
            .|:.:.|||..||.||.|  .|.|:..||:|.||.:|| ::.||.....|......:..|.:
Frog   334 PEDTFEDIITKPPVRKFV--HEKEIVAEDDQVFLMKQQSQLAKQPPAAAGRQDASPRVPGGS--- 393

  Fly   391 PRTPGTTGQS-----SP-----KKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGPG-GAG 444
            ||||..:|.:     ||     |||||.:...|. :||||||||||||.||:||||.||.| .||
Frog   394 PRTPSRSGSTNVASVSPVPTGTKKIDPNMKAGTT-SEGVLANFFNSLLSKKTGSPGAGGTGIPAG 457

  Fly   445 NPAGPGRTANGTDAVMTPEKLAVRTDAAAELDRLSR 480
            |..|....|:.......|    |.||..|||:|:||
Frog   458 NSTGNSLPASAKKTGQKP----VLTDVQAELERISR 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dlic	NP_572694.1	DLIC	25..493	CDD:283447	228/475 (48%)
Dlic	NP_572694.1	ABC_ATPase	43..>79	CDD:213179	21/35 (60%)
dync1li1	NP_001072301.1	DLIC	33..502	CDD:368612	227/471 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	417	1.000	Domainoid score	I649
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	417	1.000	Inparanoid score	I1772
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1299592at2759
OrthoFinder	1	1.000	-	-		FOG0003091
OrthoInspector	1	1.000	-	-		otm47919
Panther	1	1.100	-	-	LDO	PTHR12688
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2062
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160