Protein Alignment Lint-1 and PHF21A

DIOPT Version :9

• Sequence 1: NP_001285113.1
• Gene: Lint-1 / 32055
• FlyBaseID: FBgn0030274
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_011518459.1
• Gene: PHF21A / 51317
• HGNCID: 24156
• Length: 688
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 129/642 - (20%)
• Similarity: 230/642 - (35%)
• Gaps: 171/642 - (26%)

  Fly    36 RSLRDFLKVHALVSEVFDEQADADP---------VQMRRILDELEEEVYEINAEQQFLLLRLNDS 91
            ::|::.|||...|.:....|...||         ..:::.|.||:.::..::.:|:.::.:|..:
Human     4 QTLQEALKVEIQVHQKLVAQMKQDPQIFFLSNQNADLKKQLHELQAKITALSEKQKRVVEQLRKN 68

  Fly    92 L---QEFSVKLKENNIMFLPDIAHEYVSAQVVPLIVDPNYKIMPQSVMARDTEEMLIRKHFLLSQ 153
            |   ||...|.:   |..||...::..:||..||          |.:..:.      :.|...:|
Human    69 LIVKQEQPDKFQ---IQPLPQSENKLQTAQQQPL----------QQLQQQQ------QYHHHHAQ 114

  Fly   154 DDDSGMPPLKLSE---------LDENIPLMLAPPVRGLGQQIAAVKPEPEWLQGDEATVSVPPPP 209
            ...:..|.|..|:         ..:.:||:|.          ||....|..:.|...|::: ...
Human   115 QSAAASPNLTASQKTVTTASMITTKTLPLVLK----------AATATMPASVVGQRPTIAM-VTA 168

  Fly   210 PQSKSKLMKGSLDSTPAKRENISRSSPPPLAPI----TQTVVAELSQVPPS----PQAESPP--- 263
            ..|:..::...:.:||...:..|:.:.|....:    ..||..::...||.    ||...||
Human   169 INSQKAVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLT 233

  Fly   264 --VNF------HVVAQSRKNLQQA---LRRARKTKQQPRLFDDEEDLEITSLQNDRNKNRTSDGK 317
              .||      ..|||:...:..|   :..|.:..|:|.:........:.:.||
Human   234 PRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQN----------- 287

  Fly   318 GTPPSLEPTNAAANQAA--KKTIP--QMSSQGMAKNNTAKSKNTCRKSSPTPTSSGQSQPAVSSS 378
                |:.|......|.|  .||.|  |::|..:|...|       |.:.|....  .|:|::...
Human   288 ----SIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGT-------RLAGPQTVQ--LSKPSLEKQ 339

  Fly   379 GSSDDSSAELQQEQQRRVASAAQWRDEPRESRTQPEEYGQE-TFLGLFELYSPEVLKKLSQRHSK 442
            .....:..:.:|.:.|.:...|    .|:..|   ||..|: .|:....|.:.:.|:::..:..:
Human   340 TVKSHTETDEKQTESRTITPPA----APKPKR---EENPQKLAFMVSLGLVTHDHLEEIQSKRQE 397

  Fly   443 RKRRTVQNA--SGVDFHYGQQLNAVDAL-------------------VMGVRGQKKTKEKSEFLL 486
            |||||..|.  ||..|...::.:||..|                   |:|......|..:|....
Human   398 RKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPD 462

  Fly   487 SPTEKRLQANSKRTYTRKSK-SPDEISEKSSAGGGSGASGTASSSACQHKDGGASKCRKCRECRE 550
            ||..::    ::.|:|..:. .|..:...:|..|..            |:|       .|..||:
Human   463 SPENEK----TETTFTFPAPVQPVSLPSPTSTDGDI------------HED-------FCSVCRK 504

  Fly   551 CKRRVETEAMYCHLCSGLYHMDCHE-----FTKNRQLMQLQNSRCPPCLREKDKLEK 602
                 ..:.:.|..||.:||:||.:     ..|...:       ||.|..:..|.|:
Human   505 -----SGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWI-------CPRCQDQMLKKEE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lint-1	NP_001285113.1	PHD	548..593	CDD:214584	12/49 (24%)
PHF21A	XP_011518459.1	ING	<382..544	CDD:331088	41/196 (21%)
		PHD_PHF21A	498..540	CDD:276998	13/53 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0383
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900