| Sequence 1: | NP_572692.1 | Gene: | Lint-1 / 32055 | FlyBaseID: | FBgn0030274 | Length: | 602 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000374.1 | Gene: | AIRE / 326 | HGNCID: | 360 | Length: | 545 | Species: | Homo sapiens |
| Alignment Length: | 328 | Identity: | 62/328 - (18%) |
|---|---|---|---|
| Similarity: | 103/328 - (31%) | Gaps: | 90/328 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 284 RKTKQQPRLFDDEEDLEITSLQNDRNKNRTSDGKGTPPSLEPTNAAANQAAKKTIPQMSSQGMAK 348
Fly 349 NNTAKSKNTCRKSSP-TPTSSGQSQPAVSSSGSSDDSSAELQQEQQRRVASAAQWRDEPRESRTQ 412
Fly 413 PEEYGQETFLGLFELYSPEVLKKLSQRHSKRKRRTVQNASGVDFHYGQQLNAVDALVMGVRGQKK 477
Fly 478 TKEKSEFLLSPTEKRLQANSKRTYTRKSKSPDEI-----SEKSSAGGGSGASGTASS-------- 529
Fly 530 SACQHKDGGASKCRKCRECRECKRRVETEAMYCHLCSGLYHMDCHEFTKNRQLMQLQNS--RCPP 592
Fly 593 CLR 595 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lint-1 | NP_572692.1 | PHD | 548..593 | CDD:214584 | 8/46 (17%) |
| AIRE | NP_000374.1 | LXXLL motif 1 | 7..11 | ||
| HSR | 16..103 | CDD:460835 | 4/13 (31%) | ||
| LXXLL motif 2 | 63..67 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 101..178 | 17/81 (21%) | |||
| SAND | 197..>250 | CDD:470606 | 12/95 (13%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 234..290 | 12/65 (18%) | |||
| Interaction with histone H3 not methylated at 'Lys-4' | 295..298 | 0/2 (0%) | |||
| PHD1_AIRE | 298..340 | CDD:277014 | 11/53 (21%) | ||
| Interaction with histone H3 not methylated at 'Lys-4' | 304..312 | 1/15 (7%) | |||
| Interaction with histone H3 not methylated at 'Lys-4' | 331..335 | 0/3 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 348..382 | ||||
| LXXLL motif 3 | 414..418 | ||||
| PHD2_AIRE | 433..475 | CDD:277015 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 489..508 | ||||
| LXXLL motif 4 | 516..520 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||