Protein Alignment CDK2AP1 and CDK2AP1

DIOPT Version :9

• Sequence 1: NP_001259439.1
• Gene: CDK2AP1 / 32050
• FlyBaseID: FBgn0030269
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_004633.1
• Gene: CDK2AP1 / 8099
• HGNCID: 14002
• Length: 115
• Species: Homo sapiens
• Alignment Length: 141
• Identity: 62/141 - (43%)
• Similarity: 76/141 - (53%)
• Gaps: 35/141 - (24%)

  Fly   140 AAVAAAALSLANMCSSNGGQRNSGAGVSSTSSGSNGQSMGLNLSSSQLKYPPPSTSPVVVTTQTS 204
            |.:.||||:.|....|           .|||..::.|...| ||.    |.|||..    .||.:
Human     9 AHMPAAALNAAGSVHS-----------PSTSMATSSQYRQL-LSD----YGPPSLG----YTQGT 53

  Fly   205 ANITTPLTSTASLPSVGPGNGLTKYAQLLAVIEEMGRDIRPTYTGSRSSTERLKRGIVHARILVR 269
            .|...|               .:|||:|||:|||:|::|||||.||:|:.|||||||:|||.|||
Human    54 GNSQVP---------------QSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVR 103

  Fly   270 ECLMETERAAR 280
            |||.||||.||
Human   104 ECLAETERNAR 114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK2AP1	NP_001259439.1	CDK2AP	1..280	CDD:286844	60/139 (43%)
CDK2AP1	NP_004633.1	Interaction with CDK2AP2. /evidence=ECO:0000269|PubMed:14985111	20..25		0/4 (0%)
		CDK2AP	<62..114	CDD:370710	16/51 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4713
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003406
OrthoInspector	1	1.000	-	-		otm41789
orthoMCL	1	0.900	-	-		OOG6_109195
Panther	1	1.100	-	-	LDO	PTHR22607
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4094
SonicParanoid	1	1.000	-	-		X2302
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.730