Protein Alignment CDK2AP1 and CDK2AP2

DIOPT Version :9

• Sequence 1: NP_001259439.1
• Gene: CDK2AP1 / 32050
• FlyBaseID: FBgn0030269
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_005842.1
• Gene: CDK2AP2 / 10263
• HGNCID: 30833
• Length: 126
• Species: Homo sapiens
• Alignment Length: 118
• Identity: 52/118 - (44%)
• Similarity: 64/118 - (54%)
• Gaps: 27/118 - (22%)

  Fly   190 PPPSTSPVVVTTQTSANITT------------------PLTSTASLPSVG-------PG--NGLT 227
            |.||::|...|......:.|                  ||.:....||:|       ||  ...:
Human     8 PAPSSTPGSSTPGPGTPVPTGSVPSPSGSVPGAGAPFRPLFNDFGPPSMGYVQAMKPPGAQGSQS 72

  Fly   228 KYAQLLAVIEEMGRDIRPTYTGSRSSTERLKRGIVHARILVRECLMETERAAR 280
            .|..||:||||||::|||||.||:|:.|||||||:|||.||||||.||||.||
Human    73 TYTDLLSVIEEMGKEIRPTYAGSKSAMERLKRGIIHARALVRECLAETERNAR 125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK2AP1	NP_001259439.1	CDK2AP	1..280	CDD:286844	50/116 (43%)
CDK2AP2	NP_005842.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		7/39 (18%)
		rad23	<5..>106	CDD:273167	35/97 (36%)
		Interaction with CDK2. /evidence=ECO:0000269|PubMed:23781148	64..106		24/41 (59%)
		CDK2AP	<73..125	CDD:370710	37/51 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148264
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4713
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003406
OrthoInspector	1	1.000	-	-		otm41789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22607
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4094
SonicParanoid	1	1.000	-	-		X2302
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.830