Protein Alignment HOXA9 and hoxa9b

DIOPT Version :10

• Sequence 1: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_571608.1
• Gene: hoxa9b / 58048
• ZFINID: ZDB-GENE-000823-2
• Length: 258
• Species: Danio rerio
• Alignment Length: 277
• Identity: 136/277 - (49%)
• Similarity: 171/277 - (61%)
• Gaps: 26/277 - (9%)

Human     1 MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQSKATVFGA 65
            |:|.|.| :||.||.|  ....|:....|::.|.:.|...:..||.|:.:..|.:||:|:::|||
Zfish     1 MSTLGTL-SYYADSHL--PHENDDHLAPRFSSGPVVQQQSRELTLLEYSEQEPYTFQAKSSIFGA 62

Human    66 SWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSW-LEPTPGALSFAGLPSSRP 129
            ||:||...||:..         :|||:|  .|.:....||..:|.| |||.| ||.|.||.:...
Zfish    63 SWSPVQPTGASIA---------YHPYIH--HPCSTGDSDGASVRPWALEPLP-ALPFTGLSTDTH 115

Human   130 YGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDP- 193
            ..||.||| ...|:|   .||||.:.:....:...:| |.|.:...:.::.|......|..:||
Zfish   116 QDIKLEPL-VGSGEC---TTHTLLVAETDNNTTQTER-KVPDDAVSNGSHDEKIPAETKLDLDPS 175

Human   194 ----NNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWF 254
                :||.:|||||:|||||||||||||||||||||||||||:||||||||||||||||||||||
Zfish   176 KCNQDNPLSNWLHAKSTRKKRCPYTKHQTLELEKEFLFNMYLSRDRRYEVARLLNLTERQVKIWF 240

Human   255 QNRRMKMKKINKDRAKD 271
            |||||||||.||||.||
Zfish   241 QNRRMKMKKCNKDRPKD 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	63/192 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		9/47 (19%)
		Homeodomain	207..263	CDD:459649	54/55 (98%)
hoxa9b	NP_571608.1	Hox9_act	1..174	CDD:461369	63/192 (33%)
		Homeodomain	193..249	CDD:459649	54/55 (98%)