Protein Alignment HOXA9 and Ubx

DIOPT Version :10

• Sequence 1: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 89/298 - (29%)
• Similarity: 113/298 - (37%)
• Gaps: 110/298 - (36%)

Human     4 TGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDF-----------SPCS-- 55
            ||..||      ..|.:||:  :.|:..|.. |.|.|.:|..   ||.           ||.|
  Fly   127 TGGAGN------ANGGNAAN--ANGQNNPAG-GMPVRPSACT---PDSRVGGYLDTSGGSPVSHR 179

Human    56 -------------------FQSKATVFGA--SWN---PVHAAGANAVPAAVYHHHHHHPYVHPQA 96
                               .||...|.||  :||   .:..|.|....|:..|...:|.: :|..
  Fly   180 GGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTF-YPWM 243

Human    97 PVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGS 161
            .:|...|:        :||...:                     |.|          ||.|  |.
  Fly   244 AIAGECPE--------DPTKSKI---------------------RSD----------LTQY--GG 267

Human   162 PPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKK-RCPYTKHQTLELEKEF 225
            ...|..|:.||..          .|...|        :||.....|:: |..||::|||||||||
  Fly   268 ISTDMGKRYSESL----------AGSLLP--------DWLGTNGLRRRGRQTYTRYQTLELEKEF 314

Human   226 LFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263
            ..|.||||.||.|:|..|.|||||:||||||||||:||
  Fly   315 HTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	47/225 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		9/42 (21%)
		Homeodomain	207..263	CDD:459649	38/56 (68%)
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	37/55 (67%)