Protein Alignment HOXA9 and exex

DIOPT Version :10

• Sequence 1: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 88/333 - (26%)
• Similarity: 124/333 - (37%)
• Gaps: 99/333 - (29%)

Human    33 GTLGQPPRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHH------------ 85
            |....||......|.|...|..:..:...:..|...|..:...:|:.|...|.
  Fly   181 GAAAPPPVSPQPAANHLSHSGATMATTTLLPPAQSQPKKSFCIDALLAKSQHQSGEPQPIIVDDR 245

Human    86 ----HH-------HHPYVHPQ-----APVAAAAPDG----------RYMRSWLEPTPGALSFAGL 124
                |:       :|.:|...     |..||:|..|          |..|.:..|:|..:|.:..
  Fly   246 LAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSES 310

Human   125 PSS----------------RPYG-IKPEPLSARRGDC---------PTLDTHTLSLTDYACGSPP 163
            |:|                :|:| :.|:.||.|..|.         |...........||.|.|
  Fly   311 PTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHP- 374

Human   164 VDREKQPSEGAFSENNAENESGGDKP-PIDPN-NPA---------ANWLHAR------------- 204
               .:..::|..:.:...:.||...| |:..| .|:         |..||.|
  Fly   375 ---YQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAIL 436

Human   205 -STRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKIN--- 265
             .||:.|..:|..|.|||||:|..|.||:|.:|:|||..|.|:|.||||||||||||.|:..
  Fly   437 GKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQ 501

Human   266 ---KDRAK 270
               |:|||
  Fly   502 QEAKERAK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	43/224 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		11/53 (21%)
		Homeodomain	207..263	CDD:459649	33/55 (60%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	33/55 (60%)