Protein Alignment Klp10A and cmet

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 155/585 - (26%)
• Similarity: 260/585 - (44%)
• Gaps: 106/585 - (18%)

  Fly   279 ITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENH--KFRFDYAFNDTCDN 341
            |.||::.||..              |....|...:.|..:.|.   ::|  .:.|||.|::...|
  Fly     9 IQVCIKVRPCE--------------PGLTSLWQVKERRSIHLA---DSHAEPYVFDYVFDEGASN 56

  Fly   342 AMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMAAKDVFVTLN 406
            ..|:...||.:|....:|...|.||||||.||||:||.|:      :...|:..:|||::|..::
  Fly    57 QEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGD------EQNPGVMVLAAKEIFQQIS 115

  Fly   407 MPRYRAMNLVVSASFFEIYSGKVFDLLSDK-QKLRVLEDGKQQVQVVGLTEKVVDGVEEVLKLIQ 470
            ....|  :.::...:.|||:.|::|||:.| |.|::.|.|...|. |...|.::....::|:|:.
  Fly   116 SETER--DFLLRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVN-VNCEECIITSEVDLLRLLC 177

  Fly   471 HGNAARTSGQTSANSNSSRSHAVFQIVLRPQGS------TKIHGKFSFIDLAGNERGVDTSSADR 529
            .||..||.|:|:.|..||||||:|:|::..:.|      ..|....:.:||||:||...|.:  |
  Fly   178 LGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGA--R 240

  Fly   530 QTRM-EGAEINKSLLALKECIRALGKQSAH--LPFRVSKLTQVLRDSFIGEKSKTCMIAMISPGL 591
            ..|: ||..||||||.|...|::|.:.:.:  ..:|.||||::|:.| :|..:.|.:|..|.|
  Fly   241 GARLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQAS-LGGNAFTSIICTIKP-- 302

  Fly   592 SSCEHTLNTLRYADRVKELVVKDIVEVCPGGDT------EPIEITDDE--EEEELN--------M 640
            |..|.:.:||.:|.|.|::.:|..|.......|      ..|::..|:  |||..|        :
  Fly   303 SIMEESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQKVEHL 367

  Fly   641 VHPHSHQLH------------------------PNSHAPASQSN------NQRAPASHHSGAVIH 675
            .....|.:|                        ..||...:::.      :|....||....|..
  Fly   368 ERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPVFF 432

  Fly   676 NNNNNNNKNGN-------AGNMDLAMLS-SLSEHEMSDELIVQHQAIDDLQQ---TEEMVVEYHR 729
            :.:|...:..|       .|::|:...| |:||..:..|.|.......|:.:   |...:.:...
  Fly   433 HTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPL 497

  Fly   730 TVNATLETFLAESKALYNLTNYVDYDQ--DSYCKRGESMFSQLLDIAIQCRDMMAEYRAKLAKEE 792
            |....|.|...: |.:.:|..:...::  :..|:..:.:..:|.::..| ||.:.:  ..||::|
  Fly   498 TPKGPLTTDKIK-KEIQDLQMFTSLEKHFEVECEEVQGLKEKLAEVTAQ-RDNLEQ--ESLAEKE 558

  Fly   793  792
              Fly   559  558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	112/340 (33%)
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	113/342 (33%)
		SMC_prok_B	539..1431	CDD:274008	7/23 (30%)
		SMC_prok_B	1137..1926	CDD:274008
		YhaN	1717..2182	CDD:443752