Protein Alignment Klp10A and Klp54D

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 178/723 - (24%)
• Similarity: 307/723 - (42%)
• Gaps: 144/723 - (19%)

  Fly   102 TMAGNMLNKIQESQSIPNPIVSSNSVNTNSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQT 166
            ::|...:..::.:.|:|:  ::|:..::..::.|:....|....:.:.|.:.|  |..:|||.|.
  Fly    26 SVASTQVTMVRRASSVPH--LNSSGGSSADSAGTSGSRRGRAPVAGSRGRKTP--STTSTGQSQR 86

  Fly   167 R---IASAVP-NNTLPNPSAAASAGPAAQGVATAATTQGAGGASTRRSHALKEVERLKENREKRR 227
            :   .:|::| :.:|.|.....|   ..:|..::..|.|.||:|....:.|             |
  Fly    87 QSSGSSSSMPRSRSLTNGMRRLS---PQKGTGSSGGTGGGGGSSRNTPYFL-------------R 135

  Fly   228 ARQAEMKEEKVALMNQDPGNPNWETAQMIREYQSTLEFVPLLDGQAVDDHQITVCVRKRPISRKE 292
            :|:.|:...              :|.:::....:..|..      :..:..|.|.||.||::.||
  Fly   136 SRENEIGSA--------------DTLEIVASKSTGSEEC------STPEDNINVVVRVRPLNDKE 180

  Fly   293 VNRKEIDVISVPRKDMLI-----VHEPRSKVDLTKFLENHK------FRFDYAFNDTCDNAMVYK 346
            ...:....:..|....:|     |.:.||          |.      |.::..|........:..
  Fly   181 KRDRHGSTLQFPGNGQVILEGNDVGQKRS----------HNRDSVRVFTYNVVFEPGATQEDILD 235

  Fly   347 YTA-KPLVKTIFEGGMATCFAYGQTGSGKTHTMGGE---FNGK--VQDCKNGIYAMAAKDVFVTL 405
            |:. |.:::...||...|.|.|||||||||||:.|.   |.||  .:|.::|:...:...:|..:
  Fly   236 YSGIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLIFRSFLYLFQLI 300

  Fly   406 NMPRYRAMNLVVSASFFEIYSGKVFDLL---SDKQKLRVLEDGK------QQVQVVGLTEKVVDG 461
            .  ..:.:|.|:.|||.|||:.:|.|||   |.::.|.|....|      :.:..|...|
  Fly   301 K--NRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEE----- 358

  Fly   462 VEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGST------KIHGKFSFIDLAGNER 520
            ::::|.:::.|...|..|..:.|.:|||||.:..:.:.....|      ..|||.:|:||||:|.
  Fly   359 LDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDLAGSEL 423

  Fly   521 GVDTSSADRQTRMEGAEINKSLLALKECIRALG---KQSAHLPFRVSKLTQVLRDSFIGEKSKTC 582
            ...|.| :.:|..|...|||||:.|..||.:|.   |::.|:|:|.|:||::|.||..| ...|.
  Fly   424 TKKTMS-EGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLADSLAG-NGVTL 486

  Fly   583 MIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCP--------GGDTEPIEITDDEEEEELN 639
            |||.:||...:...||||||||.|.|.:..|.::::.|        ..|...:::.:|..:..||
  Fly   487 MIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPREALILSLKRDIHALQMENDHLKAALN 551

  Fly   640 MVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMS 704
            :    .||..||.....:....|....|...|..:             ..:||..|..|...|::
  Fly   552 L----HHQAAPNGGPVENLLELQLDRVSSGGGVPV-------------PKVDLQRLPELDGSELA 599

  Fly   705 DELIVQHQAIDDLQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMFSQ 769
            :                  :|:.:...|   |:...|:..|:.:...:..||:..|:..|.:..:
  Fly   600 E------------------LVKLYMVEN---ESLRQENNHLFTVRETILRDQEIVCRENERLLKK 643

  Fly   770 LLDIAIQC 777
            |.|:...|
  Fly   644 LEDVNKVC 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	117/364 (32%)
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	119/372 (32%)