Protein Alignment Klp10A and Kif19A

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 154/514 - (29%)
• Similarity: 237/514 - (46%)
• Gaps: 98/514 - (19%)

  Fly   272 QAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHE-----PRSKVDLTKFLENHKFRF 331
            |...:.::.|.||.||  ..|...:.|:|||   ...|:..:     ||            ::.:
  Fly    29 QPAQEERLVVAVRVRP--SMEATERCIEVIS---GGSLLYDDGGKSRPR------------QYSY 76

  Fly   332 DYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGK----------V 386
            |:.|.:......|||.|..|||:.:..|..|..||||.|||||||||.|....|          .
  Fly    77 DHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPT 141

  Fly   387 QDCKN--------GIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVLE 443
            ..|.:        |:...|.:|:|  .::....|.:..||.|:.|||:..:.|||:....|.:.|
  Fly   142 ASCDSTDVSSQDIGLMVRAIEDIF--SHIESAEAYSCRVSISYLEIYNELIRDLLNPGGPLELRE 204

  Fly   444 DGK-QQVQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLR---PQGST 504
            |.: |::.|.||:|......:||:.|:..||.|||...|:||..||||||:..|:::   |.|:.
  Fly   205 DHRGQRITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLGTK 269

  Fly   505 KIHGKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQV 569
            :  |:....||||:||...|.:..::.: |||.||:|||||...|..|...:.::.:|.||||::
  Fly   270 Q--GRLFLTDLAGSERAKKTKNRGKRLQ-EGAHINRSLLALGNVINGLSGGARYVNYRDSKLTRL 331

  Fly   570 LRDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVK-------DIVEVCPGGDTEPI 627
            |:::..| :.||.|||.::|.....:.|.|||.||||...:..|       |..:..|   |:..
  Fly   332 LKEALSG-RCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFP---TKHY 392

  Fly   628 EITDDEEEEELNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDL 692
            :....|..:|::.:........|.|.|.|:      |.|:..||:.           |.||:
  Fly   393 QSLVSELRDEVSRLRTKMLTERPRSGAAAA------AAAAAASGSA-----------GTAGS--- 437

  Fly   693 AMLSSLSEHEMSDELIVQHQAIDDLQQT------EEMVVEYHRTVNATLETFLAESKAL 745
               .:.||       .||.|  |:.::|      |::|:.:.:.:....:...|||..|
  Fly   438 ---GAGSE-------AVQEQ--DEQRKTELRYLREQIVLTFKQQMKLRRKLLEAESHLL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	123/356 (35%)
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:473979	123/358 (34%)
		SMC_prok_B	<393..672	CDD:274008	26/124 (21%)