Protein Alignment Klp10A and pav

DIOPT Version :9

• Sequence 1: NP_001285109.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 664
• Identity: 149/664 - (22%)
• Similarity: 257/664 - (38%)
• Gaps: 186/664 - (28%)

  Fly   279 ITVCVRKRPISRKEVNRKEIDVISV-----------PRKDMLIVHEPRSKVDL-TKFLENHKFRF 331
            :.|..|.||:      :.:.|:.|:           |:..:|..|:|.:.... .:::..|.|:.
  Fly    37 VNVFCRVRPL------QSDADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFKHVFQP 95

  Fly   332 DYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEF--NGKVQDCKNGIY 394
            |....|      ||...|:|||:.:.:|..:..|.||.||||||:||.|..  .|.:..|.:.::
  Fly    96 DATQQD------VYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHRGIMPRCLDVLF 154

  Fly   395 A-----MAAKDVFV--TLN-----------MPRYRAMN--------------------------- 414
            .     .|.|.||.  .||           :.|...||
  Fly   155 RTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQASVE 219

  Fly   415 ------------LVVSASFFEIYSGKVFDLLSDK------QKLRVLEDGKQQVQVVGLTEKVVDG 461
                        ..|..::.|||:..|:|||.|.      |...:.||..:.:.|.|:||..|..
  Fly   220 PIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHMFVHGVTEVEVKT 284

  Fly   462 VEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQI--VLRP---QGSTKIH-------GKFSFID 514
            ||:.|::.|.|...:..|.|..|:.|||||:||.|  |..|   ||...:.       .:.|.:|
  Fly   285 VEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNITVSQLSLVD 349

  Fly   515 LAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRAL---------GKQSAHLPFRVSKLTQVL 570
            |||:||...|.:...:.| |...||.||:.|:.|:..|         |.....:|:|.||:|.:.
  Fly   350 LAGSERSSRTKNTGVRLR-EAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKVPYRDSKITHMF 413

  Fly   571 RDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVV------KDIVEVCPG-------- 621
            ::.|.|| .:..||..|:|.:...:..:..:::|:..:|:.:      |..:.:.||
  Fly   414 KNYFDGE-GQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQIARATPMKQDLGLTPGRRKANKLF 477

  Fly   622 ----GDTEPIEITDDEE-EEELNMVHPHSHQLHPNSHAPASQSNNQRAPAS-----HHSGAVIHN 676
                .:...:.|.:.:: |.::.:|    :.|.|:  .||.:.::..|...     |:....|..
  Fly   478 KIAVNNLNELGIPEAKDLEVDVGLV----YSLGPD--FPAYEMDSPEAQIKIRELMHYLEQRIEK 536

  Fly   677 NNN-----------------NNNKNGNAGNMDLAMLSSLSEHE------MSDELIVQHQAIDDLQ 718
            ...                 |.:::......:||.|.::.:.|      :..::.:...:||.|.
  Fly   537 RKKLRANLDIKCDSFRQMLMNLDRDNLQLRTELASLKAVYKQERDRSAALEKKVRIHESSIDVLN 601

  Fly   719 QT----EEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMFSQLLDIAIQCRD 779
            .|    |..:.|.         ||....|.  |:....:::::...|:    ||..|  |::...
  Fly   602 NTLSKQERQIEEL---------TFKLNEKE--NMLTQKEHEKEKQKKK----FSSKL--AVESDK 649

  Fly   780 MMAEYRAKLAKEEM 793
            ...|:..||.::.:
  Fly   650 NKREFELKLREQRV 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_001285109.1	KISc_KIF2_like	278..608	CDD:276818	112/426 (26%)
		Kinesin	284..609	CDD:278646	111/422 (26%)
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	112/426 (26%)
		Kinesin	42..452	CDD:278646	111/423 (26%)
		MKLP1_Arf_bdg	735..837	CDD:293148

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030