Protein Alignment Klp10A and Klp59C

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 713
• Identity: 317/713 - (44%)
• Similarity: 399/713 - (55%)
• Gaps: 140/713 - (19%)

  Fly     1 MDMITVGQSVKIKRTDGRVHMA-VVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPELMQD 64
            ||.:::.|.:.|:|:|||||:| ::.:.....|.|||||.|....:|||:.|:.::.:||.:.
  Fly     1 MDKLSIEQKIFIRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIF-- 63

  Fly    65 TVEQHAAPEPKKQATAPMNLSRNPTQSAIGGNLTSRMTMAGNMLNKIQESQSIPNPIVSSNSVNT 129
                                                                             
  Fly    64 ----------------------------------------------------------------- 63

  Fly   130 NSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQTRIASAVPNNTLPNPSAAASAGPAAQGVA 194
              :|...:||...:...|.:...|....:.|||.....:|:|.|......|
  Fly    64 --DSPRCSGGNAASANQTASISPRSMKQRIATGSLSPVLATAPPRQQTAPP-------------- 112

  Fly   195 TAATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGNPNWETAQMIREY 259
                        .|....:.:.||:::.||:||..||..:.::....|:||||||||.|:|||..
  Fly   113 ------------VREDEVVHQAERMRKERERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQ 165

  Fly   260 QSTLEFVPLLDG---QAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLT 321
            :..:|...:..|   :.::.|||.|||||||:.|||:..:|.||:|:|.|..|:|||||..|:|.
  Fly   166 REQMESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLV 230

  Fly   322 KFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKV 386
            ||||||.|||||.|::.|.||.||::||:||:|.||:|||||||||||||||||:||||:|.|:.
  Fly   231 KFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRH 295

  Fly   387 QDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLL-SDKQKLRVLEDGKQQVQ 450
            |...:|||||||||||.||....|..:||.|..||||||..:||||| ..|.:||||||..||||
  Fly   296 QSSMDGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQ 360

  Fly   451 VVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKFSFIDL 515
            |||||:..|....|||.|::.||:.||||.|||||.|||||||||||||.....|:|||||.|||
  Fly   361 VVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDL 425

  Fly   516 AGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRDSFI-GEKS 579
            ||||||.|.||||||||:||:|||||||.|||||||||:||:|||||.|||||||||||| |:|.
  Fly   426 AGNERGADNSSADRQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKV 490

  Fly   580 KTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVE----------------VC--------- 619
            ||||||||||.|.|.||||||||||||||||.|:.|..                ||
  Fly   491 KTCMIAMISPCLHSVEHTLNTLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFP 555

  Fly   620 -------PGGDTEPIEITDDEEEEELNMVH-PHSHQLHPNSHAPASQSNNQRAPASHHSGAVI 674
                   |||..:..:.|:  ...:||... |.|...:|.|    .|...||..:|....:::
  Fly   556 CASSTSMPGGGNQAQQHTN--TANDLNRSQKPTSKPTYPTS----GQQLVQRKGSSQREASMM 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	234/331 (71%)
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	234/331 (71%)