Protein Alignment Klp10A and unc-104

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 167/565 - (29%)
• Similarity: 247/565 - (43%)
• Gaps: 139/565 - (24%)

  Fly   279 ITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHE--PRSKVDLTKFLENHKFRFDYAF------ 335
            :.|.||.||.:.:|:.|:...:|.:......|.:.  |.:..|..|     :|.|||::
  Fly     4 VKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVK-----RFNFDYSYWSHDHH 63

  Fly   336 -NDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMAAK 399
             .|....:||||...:.:::..|:|.....|||||||:||::||    .|:.::.:.||..|..|
  Fly    64 DADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTM----MGRQEEQQEGIIPMICK 124

  Fly   400 DVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQK--LRVLEDGKQQVQVVGLTEKVVDGV 462
            |:|..:.......:...|..|:.|||..:|.|||:.|.|  |||.|.......|..|::..|...
  Fly   125 DLFTRIQDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDY 189

  Fly   463 EEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIV-------LRPQGSTKIHGKFSFIDLAGNER 520
            :::..||..||.|||...|:.|..||||||||.|.       |....:|:...|.|.:||||:||
  Fly   190 QDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRRHDLMTNLTTEKVSKISLVDLAGSER 254

  Fly   521 GVDTSSADRQTRM-EGAEINKSLLALKECIRALG---------KQSAHLPFRVSKLTQVLRDSFI 575
            ...|.:  :.||: |||.|||||..|.:.|.||.         |::..:|:|.|.||.:||:: :
  Fly   255 ADSTGA--KGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLREN-L 316

  Fly   576 GEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIV--------------EVCPGGDTEP 626
            |..|||.|||.|||...:.:.||:|||||||.|::|.|.:|              |:....|...
  Fly   317 GGNSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAKLIRELKEEIQKLRDLLK 381

  Fly   627 IEITDDEEEEELNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMD 691
            .|..:.:||:||.                              ...||.:...:.|:||:...|
  Fly   382 AEGIEVQEEDELT------------------------------KSTVIKSPTKSRNRNGSTTEM- 415

  Fly   692 LAMLSSLSEHEMSDELIVQHQAIDDLQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQ 756
                                 |:|.||.:|:::.|    :|.|.|..|
  Fly   416 ---------------------AVDQLQASEKLIAE----LNETWEEKL----------------- 438

  Fly   757 DSYCKRGESMFSQLLDIAIQCRDMMAEYRAKLAKEEMLSCSFNSP 801
                ||.|       :|.:|...:.||....: ||:.::....||
  Fly   439 ----KRTE-------EIRVQREAVFAEMGVAV-KEDGITVGVFSP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	129/356 (36%)
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	132/365 (36%)
		Kinesin_assoc	355..498	CDD:465047	35/202 (17%)
		FHA_KIF1	474..574	CDD:438757
		YhaN	<575..>666	CDD:443752
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939