Protein Alignment Klp10A and cos

DIOPT Version :9

• Sequence 1: NP_001285109.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_001260765.1
• Gene: cos / 35653
• FlyBaseID: FBgn0000352
• Length: 1201
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 142/636 - (22%)
• Similarity: 238/636 - (37%)
• Gaps: 148/636 - (23%)

  Fly   214 KEVERLKENREKR--RARQAEMKEEKVALMNQDP-GNPNWETAQMIREYQSTLEFVPLLDGQAVD 275
            |:.:.:.|..:.:  .|:....:::..::...|| ||         .|..|..:...:.|....|
  Fly    31 KDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGN---------AEQDSAADSKTIPDANGND 86

  Fly   276 DHQ-----ITVCVRKRPISRKEVNRKEIDVISVPRKDM-------LIVHEPRSKVDLTKFLENHK 328
            ..|     ...||:..|||...:....    ::|..|.       ||...|            |.
  Fly    87 SGQKDYPDSAYCVQAIPISASALGLPS----ALPGGDPMDSIAAGLIQVGP------------HT 135

  Fly   329 FRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEF-NGKVQDCKNG 392
            ....:|...:.....||..|..||:....||..|:...|||.|.||::|:.|.. :..:.|...|
  Fly   136 VPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEG 200

  Fly   393 IYAMAAKDVF--VTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVLEDGKQQVQVVGLT 455
            :..:..:|:|  ::|:..|..|:|:    .|.||..|.|.|||                   |:.
  Fly   201 VVQLCVRDIFSHISLHPERTYAINV----GFVEICGGDVCDLL-------------------GMG 242

  Fly   456 EKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKF-------SFI 513
            ......|:.|...:|.|.:||         .|..:|.:|.:.|..|..:| .|..       ||.
  Fly   243 NIHCTNVDAVFHWLQVGLSAR---------QSLPAHTLFTLTLEQQWVSK-EGLLQHRLSTASFS 297

  Fly   514 DLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQ------SAHLPFRVSKLTQVLRD 572
            ||.|.||..|        :..|..::..|..|::.|..|...      :.::|:..:.||.:|:|
  Fly   298 DLCGTERCGD--------QPPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKD 354

  Fly   573 SFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEE 637
            || |.:::|.:|..:||.......||..|::|.:|:  .|::.|            |.:...::.
  Fly   355 SF-GGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQ--CVRNFV------------IMNTYSDDN 404

  Fly   638 LNMVHPHSHQLHPNSHA-PASQSN-----NQRAPASHHSGAVIHNNNNNNNKNGNAGNM-DLAML 695
            ..:|.|.......||.| |.||:.     ..:..||..|..|       .|..|....: |..::
  Fly   405 TMIVQPAEPVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLV-------TNAEGLFSKLIDSKLI 462

  Fly   696 SSLSEHEMSDELIVQHQAIDDLQQTEEM--------VVEYHRTVNATLETFLAESKALYNLTNYV 752
            :.:.:.::.:.|.::.:..:.|..||.|        ::|.....:...|...:||.   |..|..
  Fly   463 TEVEKEQIEEWLFLKQECEECLSSTEAMRQQKQLVPILEAEEPEDVNSEAANSESP---NSDNEN 524

  Fly   753 DYDQDSYCKRGESMFSQLLDIAIQCRDMM--------AEYRAKLAKEEMLS 795
            |.|.:|:....:.....|::   :.||..        |||.:|..|..|.|
  Fly   525 DTDNESHRPDLDDKIESLME---EFRDKTDALILEKHAEYLSKHPKAVMQS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_001285109.1	KISc_KIF2_like	278..608	CDD:276818	88/357 (25%)
		Kinesin	284..609	CDD:278646	86/347 (25%)
cos	NP_001260765.1	Motor_domain	132..389	CDD:277568	78/310 (25%)
		SPEC	657..856	CDD:295325

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030