Protein Alignment Klp10A and Klp31E

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_609398.2
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 162/666 - (24%)
• Similarity: 264/666 - (39%)
• Gaps: 185/666 - (27%)

  Fly   276 DHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHK-FRFDYAFNDTC 339
            |..:.|.||.||.:.:|:    ||:..:  ...:.:.||:.      ||.:.| |.|||.|:...
  Fly    11 DSSVRVAVRIRPQNSREL----IDMCRI--CTTVTLGEPQI------FLGSDKAFTFDYVFDTNS 63

  Fly   340 DNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKN---GIYAMAAKDV 401
            :...:|....:.||.:...|..||..||||||||||:|||..|:.:.:...:   ||...|.:.:
  Fly    64 NQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQLGIIPRAVRHI 128

  Fly   402 FVTLNM---------------PRYRAMNLVVSASFFEIYSGKVFDLLSDKQK---LRVLEDGKQQ 448
            |..:..               |::.     ::..:.|:|:..:||||....|   .::.||...|
  Fly   129 FSGIEQLEGSSTSEHPAAGGSPQFS-----LAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQ 188

  Fly   449 VQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQ------------ 501
            :.:.|.:.|.:....:.||.:|.|..|||:..|..|..||||||:|.|.:|.|
  Fly   189 ITISGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDN 253

  Fly   502 GSTKIHGKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALG---KQSAHLPFRV 563
            ....:..||.|:||||:||...|.:...:.| ||..||..||||..||.|||   |::.|:|:|.
  Fly   254 DLETLTSKFHFVDLAGSERLKRTQATGERAR-EGISINCGLLALGNCISALGDKSKRALHVPYRD 317

  Fly   564 SKLTQVLRDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEV---------- 618
            ||||::|:|| :|..|:|.|||.:||.......|||||:||:|.:.  :|:.|::
  Fly   318 SKLTRLLQDS-LGGNSQTLMIACVSPSDRDFMETLNTLKYANRARN--IKNKVKINQDQSSRTIS 379

  Fly   619 ------------------------CPGG------------------------------------- 622
                                    |.|.
  Fly   380 QLRREIAALQLELLEYKQGKLIVDCEGNTTISDTFNENKLLLSEIKRLQQRLKSLQSTIATLTQR 444

  Fly   623 ----------------DTEPIEITD-------DEEEEELNMVHPHSHQLHPNSHAPASQSNNQRA 664
                            |...:||..       :.||.:..::....|:......|..|..|.:..
  Fly   445 NADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTKLIESEEHRKQMEIKATTSPRNAKPV 509

  Fly   665 PAS----------HHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMSDELIVQHQAIDDLQQ 719
            ..|          .....::.:.:....:|.|..:.:..:.||.||   ::|::...:|||:..:
  Fly   510 YDSDIITKAKKDLERERELLMSRSLPGIQNQNVSSEETEVASSDSE---AEEVVKDLEAIDNDIE 571

  Fly   720 TEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCK-------RGESMFSQLLDIAIQC 777
            ....::|.....|:..|..         .|:|.:.....|||       |.:.:.:....::...
  Fly   572 MRTKLIEQLELTNSRYEQM---------RTHYEEKLSVLYCKIENTQKERDDVLANMTTSVSTPS 627

  Fly   778 RDMM----AEYRAKLA 789
            :|.:    .:|.:|::
  Fly   628 KDSLKKVKTDYESKIS 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	125/366 (34%)
Klp31E	NP_609398.2	KISc_KIF4	12..364	CDD:276823	125/372 (34%)
		Mplasa_alph_rch	<372..>748	CDD:275316	34/284 (12%)
		SMC_prok_B	622..>899	CDD:274008	3/22 (14%)
		Rcc_KIF21	798..870	CDD:410202