Protein Alignment Klp10A and Kif2c

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: XP_006238694.1
• Gene: Kif2c / 171529
• RGDID: 620239
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 816
• Identity: 361/816 - (44%)
• Similarity: 487/816 - (59%)
• Gaps: 131/816 - (16%)

  Fly     7 GQSVKIKRTDGRVHMAVVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPELMQ-------D 64
            |.|:.|:|::|.:|.|.::.:|....|::|||.|.|.|||||:::|.:..:||||:|       |
  Rat    11 GLSINIQRSNGLIHSANISTVNLEKSCVSVEWTEGGTTKGKEIDIDDVAAINPELVQLLPLRPKD 75

  Fly    65 TVE-QHAAPEPKKQATAPMNLSRNPTQSAIGG---NLTSRMTMAGNMLNKIQESQSIP---NPIV 122
            ::. |.....||::        |....|.|.|   .|.||.|    .::.:.|.: ||   |.:.
  Rat    76 SLPLQENVTIPKQK--------RKSVNSKIPGPKEGLRSRST----RISTVSEVR-IPAQENEME 127

  Fly   123 SSNSVNTNSNS----NTTAGGGGGTTTSTTTGLQRPRYSQAATGQ-QQTRIASAVPNNTLPNPSA 182
            ....|:|||..    :|   |....:.||.|.|.....|:.|..| ..||              :
  Rat   128 VELPVSTNSRKPFPIHT---GHPRPSCSTVTELPLLMISEEAEEQAHSTR--------------S 175

  Fly   183 AASAGPAAQGVATAATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGN 247
            .:||.|              |.:..|:|..:||:|::|..||::||:.:|::.::.  ...|...
  Rat   176 TSSANP--------------GNSVRRKSCIVKEMEKMKNKREEKRAQNSEIRIKRA--QEYDNSF 224

  Fly   248 PNWETAQMIREYQSTLEFVPLLDGQAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVH 312
            ||||.|:||:|::.|::..||.....:::|:|.|||||||::::|:.:|||||||||.|.:|:||
  Rat   225 PNWEFARMIKEFRVTMDCNPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVH 289

  Fly   313 EPRSKVDLTKFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHT 377
            ||:.||||||:|||..|.||:||::|..|.:||::||:|||:||||||.||||||||||||||||
  Rat   290 EPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHT 354

  Fly   378 MGGEFNGKVQDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVL 442
            |||:.:||.|:...||||||::|||:..|.||||::||.|..:|||||:|||||||:.|.|||||
  Rat   355 MGGDLSGKSQNASKGIYAMASRDVFLLKNQPRYRSLNLEVYVTFFEIYNGKVFDLLNKKAKLRVL 419

  Fly   443 EDGKQQVQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIH 507
            ||.|||||||||.|.:|...::|:|:|..|:|.||||||.||||||||||.|||:||.:|  ::|
  Rat   420 EDSKQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLRAKG--RLH 482

  Fly   508 GKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRD 572
            ||||.:||||||||.|||||||||||||||||||||||||||||||:..||.|||.|||||||||
  Rat   483 GKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRD 547

  Fly   573 SFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEE 637
            |||||.|:||||||||||:||||:||||||||||||||
  Rat   548 SFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKEL--------------------------- 585

  Fly   638 LNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHE 702
                .|||..    |...|.|...:...||.|.                      |.|:...|.|
  Rat   586 ----SPHSGP----SGEQAVQMETEEMDASSHG----------------------ASLTGNEEEE 620

  Fly   703 MSDELIVQHQAIDDLQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMF 767
            :|.::...::|:..:::.||..:|..|.:.....::|    .|..:|:..|||.:::..:.||..
  Rat   621 LSSQMSSFNEAMTQIRELEERAMEELREIIQQGPSWL----ELSEMTDQPDYDLETFVNKAESAL 681

  Fly   768 SQLLDIA---IQCRDMMAEYRAKLAKEEMLSCSFNS 800
            :|....|   ...::::...|..:..||..|...||
  Rat   682 TQQAKQAKHFSALQEVIKALRLAMQLEEQASKQINS 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	238/329 (72%)
Kif2c	XP_006238694.1	KISc_KIF2_like	255..583	CDD:276818	238/329 (72%)