Protein Alignment Klp10A and Klp10A

DIOPT Version :10

• Sequence 1: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: XP_061500511.1
• Gene: Klp10A / 1272103
• VectorBaseID: AGAMI1_004182
• Length: 904
• Species: Anopheles gambiae
• Alignment Length: 859
• Identity: 419/859 - (48%)
• Similarity: 533/859 - (62%)
• Gaps: 157/859 - (18%)

  Fly    18 RVHMAVVAVINQSGKCITVEWYERGETKGKEVELDAILTLN------PELMQD------------ 64
            |:|.|:|:..::..:.:|||||||||:||||:|:|.:|.||      |:|.|:
Mosquito   113 RIHTAIVSRFHEDTRSVTVEWYERGESKGKEIEIDMLLELNRTMQLQPQLQQELHHQQQHQHQQH 177

  Fly    65 --TVEQHAAPEPK---------KQATAPMNLSR-----------------NPTQSAIGGNLTSRM 101
              ..:|...||||         |:..||.||:|                 ||||:.|..|
Mosquito   178 YQQQQQQHEPEPKPTAEEAKQRKKTPAPANLARRSSSIEDEEDTSQPEQTNPTQAIIRYN----- 237

  Fly   102 TMAGNMLNKIQES---QSIPNPIVSSN-----SVNTNSNSNTTAGGGGGTT--------TSTTTG 150
                |.|.:..:|   .|||.|   ||     .::|.....:...|.|.||        .|..||
Mosquito   238 ----NYLAQRGDSGKGASIPAP---SNFNRATILHTGPTQRSEQSGTGRTTNVSSRILGNSNNTG 295

  Fly   151 ---------LQRPRYSQ----------AATGQQQTRIASAVPNNTLPNPSAAASAGPAAQGVATA 196
                     .::|..::          .|||||||...:|          |||:|.||:   |.|
Mosquito   296 RSTMINNRAAEQPAETRTQPKALGKTSVATGQQQTTAPAA----------AAAAAAPAS---AVA 347

  Fly   197 ATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGNPNWETAQMIREYQS 261
            ........:..|:|..:..|..::|||.|:|.....|:|:|.||||||.||||||...|||||||
Mosquito   348 NANNAVANSIPRKSSCVVTVGMMEENRIKQRDMFKVMREKKNALMNQDGGNPNWEFINMIREYQS 412

  Fly   262 TLEFVPLLDGQAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLEN 326
            |::|.||:.||::|.|||||||||||:::||..|||:||:.:|.||.:|||||::||||||:|:|
Mosquito   413 TIDFRPLVQGQSIDQHQITVCVRKRPLNQKEQTRKEVDVVCIPNKDTVIVHEPKAKVDLTKYLDN 477

  Fly   327 HKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKN 391
            .|||||..|:|||.|.|||.|||||||:.:|||.||||||||||||||||||||.||||.||..|
Mosquito   478 QKFRFDCTFDDTCSNEMVYMYTAKPLVQAVFEGAMATCFAYGQTGSGKTHTMGGTFNGKSQDSMN 542

  Fly   392 GIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVLEDGKQQVQVVGLTE 456
            ||||:|.:|:|..|..|:|::.||||||||:|||.|.|:|||::|.|.|||||||:|||||||||
Mosquito   543 GIYALATRDIFELLQSPKYQSNNLVVSASFYEIYCGNVYDLLANKNKARVLEDGKKQVQVVGLTE 607

  Fly   457 KVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKFSFIDLAGNERG 521
            :.|:.|:|||.:|..|:..||||||:||||||||||:|.:.||.|.|.|:|||||||||||||||
Mosquito   608 REVNSVDEVLAIISSGSNLRTSGQTAANSNSSRSHAIFSLTLRVQASPKVHGKFSFIDLAGNERG 672

  Fly   522 VDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRDSFIGEKSKTCMIAM 586
            .||.|.:|:||.|.:|||||||:|||||||||:: .|||:|.|.||:||||||:|:..:||||||
Mosquito   673 ADTVSENRRTRSESSEINKSLLSLKECIRALGRK-RHLPYRGSVLTKVLRDSFVGKNIRTCMIAM 736

  Fly   587 ISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEELNMVHPHSHQLHPN 651
            |:||::||||||||||||.|||||.|.|     |....:|       ||:.:....|
Mosquito   737 IAPGMASCEHTLNTLRYAHRVKELAVVD-----PDDRVDP-------EEDLIECDEP-------- 781

  Fly   652 SHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMSDELIVQHQAIDD 716
                                    :|...:|.|      ||..|.||:|.||:.||..||:||.|
Mosquito   782 ------------------------SNGGTHNFN------DLEQLRSLNEQEMTMELYNQHKAISD 816

  Fly   717 LQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMFSQLLDIAIQCRDMM 781
            |||.||.|::.|:.||..||.||.|:|.|||.||.||||||:||||||.:||||.::|...:|:|
Mosquito   817 LQQKEEEVLDNHQRVNEFLEKFLPEAKELYNFTNLVDYDQDAYCKRGEELFSQLAEVANAFKDLM 881

  Fly   782 AEYRAKLAKEEMLS 795
            :|:|.||::||::|
Mosquito   882 SEFRTKLSQEEIVS 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	230/329 (70%)
Klp10A	XP_061500511.1	None