Protein Alignment Klp10A and kif2c

DIOPT Version :9

• Sequence 1: NP_001285109.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: XP_005163529.1
• Gene: kif2c / 100136875
• ZFINID: ZDB-GENE-070912-298
• Length: 700
• Species: Danio rerio
• Alignment Length: 668
• Identity: 310/668 - (46%)
• Similarity: 410/668 - (61%)
• Gaps: 80/668 - (11%)

  Fly     1 MDMITVGQSVKIKRTDGRVHMAVVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPEL---M 62
            :..:.:|.:|.|.|:|||:|.|:|...|.|...:.|||.|.|.||||||:::.:..||.:|   :
Zfish     5 LSKLLIGLAVNISRSDGRIHSAIVKTANVSKSTVNVEWAEHGMTKGKEVDMNELNHLNSDLIQHL 69

  Fly    63 QDTVEQHAAPEP-----------KKQATAPMNLSRNPTQSAIGGN-------LTSRMTMAGNMLN 109
            |...::..||.|           .|.:..|:..||.||.|.....       .:.|||.....|.
Zfish    70 QPCHQEEPAPTPIPTPMTRMTKSVKASELPLRSSRIPTTSEPAPRDCPSEEPASRRMTTRQTCLF 134

  Fly   110 KIQESQSIPNPIVSSNSVNTNSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQTRIASAVPN 174
            :    |..|.|:||::|.:...:.|..:     :|....:|.||             |:.|...:
Zfish   135 R----QPAPPPVVSASSADDVLSQNLPS-----STIPKHSGYQR-------------RLLSKPAS 177

  Fly   175 NTLPNPSA--------AASAGPAAQGVATAATTQGAGGASTRRSHALKEVERLKENREKRRARQA 231
            ..||:..|        .|..||.:..::..:.|...         |.|.:...|....::|.:..
Zfish   178 PLLPSTEAICESEASKCAPMGPPSHRMSQVSETNKV---------ANKRLSIAKMPDAQKRGKFG 233

  Fly   232 EMKEEKVALMNQDPGNPNWETAQMIREYQSTLEFVPLLDGQAVDDHQITVCVRKRPISRKEVNRK 296
            |....|             :..|||.||:.|::.||:.....|..|:|.|||||||:::||:.:|
Zfish   234 ETNRSK-------------QFYQMIEEYRETVQKVPMSLSDPVKTHRICVCVRKRPLNKKELAKK 285

  Fly   297 EIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGM 361
            ||||:::|...:|::|||:.||||||:|||..|.|||:|::...|.:||::||||||||||||||
Zfish   286 EIDVVTIPGNGVLLLHEPKQKVDLTKYLENQTFHFDYSFDEDATNDLVYRFTAKPLVKTIFEGGM 350

  Fly   362 ATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYS 426
            |||||||||||||||||||:|:||.|:...||||:||:|||..|...||..|:|....:|||||:
Zfish   351 ATCFAYGQTGSGKTHTMGGDFSGKSQNSSKGIYALAAQDVFTLLRQKRYVDMDLCPYVTFFEIYN 415

  Fly   427 GKVFDLLSDKQKLRVLEDGKQQVQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSH 491
            |||||||:.|.|||||||.||||.||||.|..|..|::|:|:|:.|:|.||||||.||::|||||
Zfish   416 GKVFDLLNKKTKLRVLEDEKQQVNVVGLQEVPVSCVDDVIKMIERGSACRTSGQTFANASSSRSH 480

  Fly   492 AVFQIVLRPQGSTKIHGKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQS 556
            |:.|::||.:..  ::||||.:||||||||.|.||.||.|.:|.||||:||||||||||:||:.|
Zfish   481 AILQVILRRRNF--LYGKFSLVDLAGNERGTDVSSNDRHTIVETAEINRSLLALKECIRSLGQNS 543

  Fly   557 AHLPFRVSKLTQVLRDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKEL--VVK-DIVEV 618
            .|:|||:||||||||||||||.|:||||||||||:||||:||||||||:|||||  :.| |.||
Zfish   544 EHIPFRMSKLTQVLRDSFIGENSRTCMIAMISPGMSSCEYTLNTLRYANRVKELNGISKGDAVE- 607

  Fly   619 CPGGDTEPIEITDDEEEE 636
             .|...|..|..:..|||
Zfish   608 -NGSKLELSEEGNSSEEE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp10A	NP_001285109.1	KISc_KIF2_like	278..608	CDD:276818	219/329 (67%)
		Kinesin	284..609	CDD:278646	216/324 (67%)
kif2c	XP_005163529.1	KISc_KIF2_like	267..595	CDD:276818	219/329 (67%)
		Kinesin	273..596	CDD:278646	216/324 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	485	1.000	Domainoid score	I382
eggNOG	1	0.900	-	-		E2759_KOG0246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	1	1.000	-	-		FOG0001531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	1	1.100	-	-	O	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X866
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.780