Protein Alignment Rpt3 and PSMC4

DIOPT Version :9

• Sequence 1: NP_001285108.1
• Gene: Rpt3 / 32047
• FlyBaseID: FBgn0028686
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_006494.1
• Gene: PSMC4 / 5704
• HGNCID: 9551
• Length: 418
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 360/413 - (87%)
• Similarity: 382/413 - (92%)
• Gaps: 7/413 - (1%)

  Fly     8 LIPEK--DELSDLKLKDAHSSLDEL-----DMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKK 65
            ::.||  ||:..|.:....:.|..|     |:||||.||||||:.|||:|||||||||||:||||
Human     6 ILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKK 70

  Fly    66 EYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKH 130
            |:||||||||||||:|||||||||||||||.|||||||||||||||||||||||||:||||||||
Human    71 EFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKH 135

  Fly   131 SNALVDVLPPEADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPR 195
            ||||||||||||||||.||..|:||||.||||||||:||||:|||||||||||||||||||||||
Human   136 SNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPR 200

  Fly   196 GVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 260
            |||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||
Human   201 GVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 265

  Fly   261 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRK 325
            ||||||||||||||||||||||||||||||||||||..|||||||||||||||||||||||||||
Human   266 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRK 330

  Fly   326 IEFPLPDRRQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVL 390
            |||||||||||||:||||||||||||:||||::|||||||||||||:||||:||.||||||||||
Human   331 IEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVL 395

  Fly   391 AKDFEKGYKNNIKKDEQEHEFYK 413
            ||||||.||..||||||||||||
Human   396 AKDFEKAYKTVIKKDEQEHEFYK 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	353/395 (89%)
		AAA	197..330	CDD:278434	129/132 (98%)
PSMC4	NP_006494.1	PTZ00454	34..418	CDD:240423	351/383 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145070
Domainoid	1	1.000	262	1.000	Domainoid score	I1962
eggNOG	1	0.900	-	-		E1_COG1222
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4744
Inparanoid	1	1.050	705	1.000	Inparanoid score	I663
Isobase	1	0.950	-	0	Normalized mean entropy	S94
OMA	1	1.010	-	-		QHG54142
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	1	1.000	-	-		FOG0004043
OrthoInspector	1	1.000	-	-		oto88915
orthoMCL	1	0.900	-	-		OOG6_101965
Panther	1	1.100	-	-	LDO	PTHR23073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1000
SonicParanoid	1	1.000	-	-		X2788
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750