DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt3 and psmc1b

DIOPT Version :9

Sequence 1:	NP_001285108.1	Gene:	Rpt3 / 32047	FlyBaseID:	FBgn0028686	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001002091.1	Gene:	psmc1b / 415181	ZFINID:	ZDB-GENE-040625-69	Length:	440	Species:	Danio rerio

Alignment Length:	390	Identity:	195/390 - (50%)
Similarity:	280/390 - (71%)	Gaps:	17/390 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LKLKDAHSSLDELDMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPL 82
            |||.......|.|.||:.::|.::..|.||  |.|||               .:.:|..::..|:
Zfish    60 LKLLKQDRIKDYLLMEEEFIRNQEQMKPLE--EKQEE---------------ERSKVDDLRGTPM 107

  Fly    83 VIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSIS 147
            .:|...|.:|.|..||.::.||.:||.|||.:|::||:|..||.|:...:|::.||..:.|..::
Zfish   108 SVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVT 172

  Fly   148 MLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 212
            :::.::.|..:||||||:|.|.|||:|:|||||||.|.|:::||.||:||::||.||.|||:|||
Zfish   173 VMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGAPGTGKTLLAK 237

  Fly   213 AVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGAD 277
            |||:.|:|:|:||||||.:|||||:||::||::||:|:|:||:|:||||||||.|||:|:.:|.:
Zfish   238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302

  Fly   278 REVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFST 342
            ||:||.:||||||:||||...:|||||||||.:||||||:||||:||||||||||.:.||.:|..
Zfish   303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFQI 367

  Fly   343 ITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKNNIKKDEQ 407
            .||:|.::|||.|::.:...|.:|||||.|||.|||:.|:||.|..|..:||:|..:|.:.|.::
Zfish   368 HTSRMTVAEDVSLDDLILAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQE 432

Fly 408 407
Zfish 433 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	192/386 (50%)
Rpt3	NP_001285108.1	AAA	197..330	CDD:278434	91/132 (69%)
psmc1b	NP_001002091.1	PTZ00361	1..440	CDD:185575	195/390 (50%)
		Prot_ATP_ID_OB	108..>176	CDD:293059	24/67 (36%)
		AAA	222..355	CDD:278434	91/132 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920