DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt3 and psmc1a

DIOPT Version :9

Sequence 1:	NP_001285108.1	Gene:	Rpt3 / 32047	FlyBaseID:	FBgn0028686	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_956327.1	Gene:	psmc1a / 336786	ZFINID:	ZDB-GENE-030131-8730	Length:	440	Species:	Danio rerio

Alignment Length:	397	Identity:	190/397 - (47%)
Similarity:	289/397 - (72%)	Gaps:	10/397 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DELSDLKLKDAHSSLDELDMEDLYVRYKKLQKTLEFIEVQEEYIKDEQ--RNLKKEYLHAQEEVK 75
            |..|.|.|...|:        ...::..|.::..:::.::||:|:|::  :.|:::....:.:|.
Zfish    44 DAASKLPLVTPHT--------QCRLKLLKQERIKDYLLMEEEFIRDQEQMKPLEEKQEEERSKVD 100

  Fly    76 RIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPP 140
            .::..|:.:|...|.:|.|..||.::.||.:||.|||.:|::||:|..||.|:...:|::.||..
Zfish   101 DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMD 165

  Fly   141 EADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGC 205
            :.|..:::::.::.|..:||||||:|.|.|||:|:|||||||.|.|:::||.||:||::||.||.
Zfish   166 DTDPLVTVMKVEKAPQETYADIGGLDSQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGAPGT 230

  Fly   206 GKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRF 270
            |||:||||||:.|:|:|:||||||.:|||||:||::||::||:|:|:||:|:||||||||.|||:
Zfish   231 GKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRY 295

  Fly   271 DAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 335
            |:.:|.:||:||.:||||||:||||...:|||||||||.:||||||:||||:||||||||||.:.
Zfish   296 DSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT 360

  Fly   336 KRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKN 400
            ||.:|...||:|.:::||.|::.:...|.:|||||.|||.|||:.|:||.|..|..:||:|..:|
Zfish   361 KRRIFQIHTSRMTVADDVTLDDLILAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKEN 425

  Fly   401 NIKKDEQ 407
            .:.|.::
Zfish   426 VLYKKQE 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	186/388 (48%)
Rpt3	NP_001285108.1	AAA	197..330	CDD:278434	91/132 (69%)
psmc1a	NP_956327.1	PTZ00361	25..440	CDD:185575	190/397 (48%)
		Prot_ATP_ID_OB	108..>176	CDD:293059	24/67 (36%)
		AAA	222..355	CDD:278434	91/132 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920