DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt3 and Psmc1

DIOPT Version :9

Sequence 1:	NP_001285108.1	Gene:	Rpt3 / 32047	FlyBaseID:	FBgn0028686	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_476464.1	Gene:	Psmc1 / 117263	RGDID:	621097	Length:	440	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	191/397 - (48%)
Similarity:	291/397 - (73%)	Gaps:	10/397 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DELSDLKLKDAHSSLDELDMEDLYVRYKKLQKTLEFIEVQEEYIKDEQ--RNLKKEYLHAQEEVK 75
            |..|.|.|...|:        ...::..||::..:::.::||:|::::  :.|:::....:.:|.
  Rat    44 DAASKLPLVTPHT--------QCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVD 100

  Fly    76 RIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPP 140
            .::..|:.:|...|.:|.|..||.::.||.:||.|||.:|::||:|..||.|:...:|::.||..
  Rat   101 DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMD 165

  Fly   141 EADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGC 205
            :.|..:::::.::.|..:||||||:|.|.|||:|:|||||||.|.|:::||.||:||::|||||.
  Rat   166 DTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGT 230

  Fly   206 GKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRF 270
            |||:||||||:.|:|:|:||||||.:|||||:||::||::||:|:|:||:|:||||||||.|||:
  Rat   231 GKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRY 295

  Fly   271 DAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 335
            |:.:|.:||:||.:||||||:||||...:|||||||||.:||||||:||||:||||||||||.:.
  Rat   296 DSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT 360

  Fly   336 KRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKN 400
            |:.:|...||:|.|::||.|::.:...|.:|||||.|||.|||:.|:||.|..|..:||:|..:|
  Rat   361 KKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKEN 425

  Fly   401 NIKKDEQ 407
            .:.|.::
  Rat   426 VLYKKQE 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	187/388 (48%)
Rpt3	NP_001285108.1	AAA	197..330	CDD:278434	92/132 (70%)
Psmc1	NP_476464.1	PTZ00361	1..440	CDD:185575	191/397 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..104		2/19 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920