DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpt3 and Psmc4

DIOPT Version :9

Sequence 1:	NP_001285108.1	Gene:	Rpt3 / 32047	FlyBaseID:	FBgn0028686	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_476463.1	Gene:	Psmc4 / 117262	RGDID:	621102	Length:	418	Species:	Rattus norvegicus

Alignment Length:	413	Identity:	360/413 - (87%)
Similarity:	382/413 - (92%)	Gaps:	7/413 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LIPEK--DELSDLKLKDAHSSLDEL-----DMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKK 65
            ::.||  ||:..|.:....:.|..|     |:||||.||||||:.|||:|||||||||||:||||
  Rat     6 ILVEKIQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKK 70

  Fly    66 EYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKH 130
            |:||||||||||||:|||||||||||||||.|||||||||||||||||||||||||:||||||||
  Rat    71 EFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKH 135

  Fly   131 SNALVDVLPPEADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPR 195
            ||||||||||||||||.||..|:||||.||||||||:||||:|||||||||||||||||||||||
  Rat   136 SNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPR 200

  Fly   196 GVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 260
            |||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||
  Rat   201 GVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 265

  Fly   261 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRK 325
            ||||||||||||||||||||||||||||||||||||..|||||||||||||||||||||||||||
  Rat   266 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRK 330

  Fly   326 IEFPLPDRRQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVL 390
            |||||||||||||:||||||||||||:||||::|||||||||||||:||||:||.||||||||||
  Rat   331 IEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVL 395

  Fly   391 AKDFEKGYKNNIKKDEQEHEFYK 413
            ||||||.||..||||||||||||
  Rat   396 AKDFEKAYKTVIKKDEQEHEFYK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	353/395 (89%)
Rpt3	NP_001285108.1	AAA	197..330	CDD:278434	129/132 (98%)
Psmc4	NP_476463.1	PTZ00454	34..418	CDD:240423	351/383 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338779
Domainoid	1	1.000	262	1.000	Domainoid score	I1883
eggNOG	1	0.900	-	-		E1_COG1222
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4744
Inparanoid	1	1.050	706	1.000	Inparanoid score	I628
OMA	1	1.010	-	-		QHG54142
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	1	1.000	-	-		FOG0004043
OrthoInspector	1	1.000	-	-		oto96047
orthoMCL	1	0.900	-	-		OOG6_101965
Panther	1	1.100	-	-	LDO	PTHR23073
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2788
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770