Protein Alignment Hsp60A and groL

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_418567.1
• Gene: groL / 948665
• ECOCYCID: EG10599
• Length: 548
• Species: Escherichia coli
• Alignment Length: 551
• Identity: 294/551 - (53%)
• Similarity: 408/551 - (74%)
• Gaps: 5/551 - (0%)

  Fly    23 AKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQ 87
            ||||:||.:.|..||:||:||||||.||:|||||||::::|:|:|.||||||:||:.|||:|||:
E. coli     3 AKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFE 67

  Fly    88 NIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLK 152
            |:||::|::||:..|:.||||||||||||:||..||.:.::.|.||::::||:..||....:.||
E. coli    68 NMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELK 132

  Fly   153 TMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVITVKDGKTLTDELEVIEGMKFDR 217
            .:|.|.|..:.||||.|||||.|:.:|.||:|||.|||::|||||:||..|.|||:|:|||:|||
E. coli   133 ALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDR 197

  Fly   218 GYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTL 282
            ||:||||||..:...||.:...:||::||||:::.::|.||......|||:|||||::||||:||
E. coli   198 GYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATL 262

  Fly   283 VVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVIT 347
            |||.::..::|||||||||||.||:.|.|:|..:||.|..::..: :||...:.||||...|||.
E. coli   263 VVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGM-ELEKATLEDLGQAKRVVIN 326

  Fly   348 KDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNE 412
            ||.|.::.|.|::..:..|..||:.|||:.||:|::||||||:|:||.|||:::||.::|||:.|
E. coli   327 KDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKE 391

  Fly   413 KKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVETTNEDQKLGVEIVRRALRMPCMTIAK 477
            ||.||.|||:|||||||||:|.|||.||:|...||..:...||||.:|:::..||:..|...|..
E. coli   392 KKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVL 456

  Fly   478 NAGVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVV 542
            |.|.:.::|...|:...|:|||:|...||||:|:.||:|||||.|:|:..|:.||.|:.|.|.:|
E. coli   457 NCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMV 521

  Fly   543 TEIPKEDGAPAMPGMGGMGGMGGMGGMGGMM 573
            |::||.|.|    .:|..|||||||||||||
E. coli   522 TDLPKNDAA----DLGAAGGMGGMGGMGGMM 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	274/519 (53%)
groL	NP_418567.1	groEL	2..530	CDD:234573	279/527 (53%)