Protein Alignment Hsp60A and CCT6

DIOPT Version :9

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_010474.3
• Gene: CCT6 / 851768
• SGDID: S000002596
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 574
• Identity: 138/574 - (24%)
• Similarity: 230/574 - (40%)
• Gaps: 125/574 - (21%)

  Fly    43 LADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGD 107
            |...:...:||||...::....|:.|:||||..:...:::    |:..|.|:...|...:|..||
Yeast    29 LQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQI----QSPTAVLIARAAAAQDEITGD 89

  Fly   108 GTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLA-VETVK--DNLKTMSRPVSTPEE-IAQVA 168
            ||||...|...:.::....|.:|.:|..|..|..:| .|::|  |..|.....:|...| :.|||
Yeast    90 GTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVA 154

  Fly   169 TIS----ANGDQAIGNLISEAMKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSK 229
            ..|    .:.|      ::|.:..:..|.|::|.|.:....:|.::|.|:..  ::||
Yeast   155 RSSLLTKVDAD------LTEVLTPIVTDAVLSVYDAQADNLDLHMVEIMQMQ--HLSP------- 204

  Fly   230 GAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNR----LKIG 290
                  :|.             :.|..|.|.:..|.|           .:.|.|.|.    |.:.
Yeast   205 ------KDT-------------TFIKGLVLDHGGRHP-----------DMPTRVKNAYVLILNVS 239

  Fly   291 LQVAAVKA-PGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLG---QVGEVVITKD-- 349
            |:....:. .||..:.......:|.:....|   ||.|.|:.|:|....|   ..|.|:|.:.
Yeast   240 LEYEKTEVNSGFFYSSADQRDKLAASERKFV---DAKLKKIIDLKNEVCGMDPDKGFVIINQKGI 301

  Fly   350 DTLLLKGKGKKDDV-LRRA-------------NQIKDQIEDTTSE--------YEKEKLQERLAR 392
            |.:.|....|.:.: ||||             .:.::.:||.:.:        |::...:|:...
Yeast   302 DPMSLDVFAKHNILALRRAKRRNMERLQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTY 366

  Fly   393 LASGV----ALLRVGGSSEVEVNEKKDRVHDALNATRAAV-EEGIVPGGGT---ALLRCI----- 444
            :....    ..:.:.||:...:.:.||.|.|.|.|....: ::.|:||.|.   ||.|.:
Yeast   367 VTENTDPKSCTILIKGSTHYALAQTKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANM 431

  Fly   445 EKLEGVETTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGD---------YGYD 500
            .||.....|    |.|:|....||.:...|:.||:|.|...|:|.||::..|         .|.|
Yeast   432 NKLGAKGKT----KTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVD 492

  Fly   501 ALKGEYGNLIEKGIIDPTKVVRTAITDASGVAS-------LLTTAEAVVTEIPK 547
            ...|:..:...:||.|..:|:|.|||.|:|:||       ||....:.:.|.|:
Yeast   493 LNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	138/574 (24%)
		GroEL	24..544	CDD:239460	136/569 (24%)
CCT6	NP_010474.3	chap_CCT_zeta	2..542	CDD:274088	136/568 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810