Protein Alignment Hsp60A and Hspd1

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_071565.2
• Gene: Hspd1 / 63868
• RGDID: 621314
• Length: 573
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 429/577 - (74%)
• Similarity: 500/577 - (86%)
• Gaps: 9/577 - (1%)

  Fly     1 MFRLPVSLAR-SSISRQLA---MRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIE 61
            |.|||..|.: ..:||.||   .|.|||||:||.:.||:||||||:||||||||||||||.||||
  Rat     1 MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIE 65

  Fly    62 QSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEK 126
            |||||||:|||||||||||:||||::||||||||||||||||||||||||||||||:||||||||
  Rat    66 QSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEK 130

  Fly   127 ISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGR 191
            ||||||||||||||||||:.|...||..|:||:||||||||||||||||:.|||:||:|||||||
  Rat   131 ISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGR 195

  Fly   192 DGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPA 256
            .|||||||||||.||||:|||||||||||||||||:|||.|.|||||.:|||||||||||||:||
  Rat   196 KGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPA 260

  Fly   257 LELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVF 321
            ||:|||.||||||||||:|||||||||:||||:||||.||||||||||||:.|.|||||:||.||
  Rat   261 LEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVF 325

  Fly   322 GDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKL 386
            |::...:.||||:..|||:||||::||||.:||||||.|..:.:|..:|.:|::.||||||||||
  Rat   326 GEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKL 390

  Fly   387 QERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVE 451
            .||||:|:.|||:|:|||:|:||||||||||.|||||||||||||||.|||.||||||..|:.::
  Rat   391 NERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLK 455

  Fly   452 TTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIID 516
            ..|||||:|:||::|||::|.|||||||||:|:::|.|:...:.:.||||:.|::.|::||||||
  Rat   456 PANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIID 520

  Fly   517 PTKVVRTAITDASGVASLLTTAEAVVTEIPKEDGAPAMPGMGGMGGMGGMGGMGGMM 573
            ||||||||:.||:|||||||||||||||||||:   ..||||.|||||  |||||.|
  Rat   521 PTKVVRTALLDAAGVASLLTTAEAVVTEIPKEE---KDPGMGAMGGMG--GGMGGGM 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	396/519 (76%)
Hspd1	NP_071565.2	GroEL	28..548	CDD:239460	396/519 (76%)