DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsp60A and Bbs10

DIOPT Version :9

Sequence 1:	NP_511115.2	Gene:	Hsp60A / 32045	FlyBaseID:	FBgn0015245	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001102756.1	Gene:	Bbs10 / 500832	RGDID:	1560748	Length:	713	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	37/203 - (18%)
Similarity:	76/203 - (37%)	Gaps:	53/203 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNT 101
            |:..:||.......:||:|..|:..:..|...:::||..:.:::.|:...    |:::....::.
  Rat    11 LRVAEVLETIANRCVGPEGGLVLCTKPTGEVLLSRDGGCLLEALHLEHPL----ARMIVACVSSH 71

  Fly   102 NEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEI-- 164
            .::.|||..|..:..                 ..:.||:....|..||:.        |.|:|
  Rat    72 LKKTGDGAKTFIIFL-----------------CHLLRGLHAIGEKEKDSF--------TSEDIQS 111

  Fly   165 --------AQVATISAN----GDQAIGNLISEAMKKVGRDGVITVKDGKTL-TDELEVIEGMKFD 216
                    .|..:||..    ..|.:|.::.:.:.:.......:..:|:|| ...||::
  Rat   112 HERHWKNCCQWKSISRALLRFQTQTLGCIVDQHLSRHYLSAFSSSAEGRTLCRRSLELL------ 170

  Fly   217 RGYISPYF 224
               :.|||
  Rat   171 ---LEPYF 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	37/203 (18%)
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	37/203 (18%)
Bbs10	NP_001102756.1	chaperonin_like	7..>94	CDD:295468	18/103 (17%)
		Cpn60_TCP1	13..>424	CDD:278544	36/201 (18%)
		Glyco_tranf_GTA_type	<589..>673	CDD:299700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900