Protein Alignment Hsp60A and Hsp60B

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 370/597 - (61%)
• Similarity: 457/597 - (76%)
• Gaps: 27/597 - (4%)

  Fly     1 MFRLPVSLARSSISRQLAMRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWG 65
            |||..|..|.:| ||..| |.|:||||||..|||||::|||:||||||||||||||:||:|:.|.
  Fly     1 MFRSCVPKAITS-SRCFA-RMYSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWT 63

  Fly    66 SPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKG 130
            ||||||||.|||:||.|||:..|:|||||||||:||||.||||||||||||||||||||.:|:.|
  Fly    64 SPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMG 128

  Fly   131 ANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVI 195
            ||||||||||||||:.|||.||.||:.|.|.|||.||||:|||||..||.||.||..|||..|.|
  Fly   129 ANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTI 193

  Fly   196 TVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELA 260
            ||||||.|.|||.:|:|::||.||:||:|:|||||:||||.:||:::|.|||:.:..|:..||.:
  Fly   194 TVKDGKRLKDELNIIQGLRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQS 258

  Fly   261 NAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDA 325
            ..||:||:||||||.||||:.||:|:|::||||.|||:|.:|.:||..:.|::.|:|..:||||.
  Fly   259 LRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDI 323

  Fly   326 DLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQI-EDTTSEYEKEKLQER 389
            :..|:|:.|:.|||||||.||:||.|:||:||.|...:..|..||:|:: |......::::|::|
  Fly   324 NYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQR 388

  Fly   390 LARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVETTN 454
            |:.|..|||:|.:||.||||||||||||.|||||||||:|||||||||||.||||..|:.::|.:
  Fly   389 LSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELKTES 453

  Fly   455 EDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIIDPTK 519
            .|.:.||:||..||||||.|||:||||||.||||||.|.:.||||||:..||..|:|||||||||
  Fly   454 ADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSEDYGYDAMGDEYCRLVEKGIIDPTK 518

  Fly   520 VVRTAITDASGVASLLTTAEAVVTEIPKED------GA------------------PAMPGMGGM 560
            |:|||||||:||||||:|.|.|:|:...:|      ||                  .|:.|:|||
  Fly   519 VLRTAITDAAGVASLLSTTEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGM 583

  Fly   561 GGMGGMGGMGGM 572
            ||||||||||||
  Fly   584 GGMGGMGGMGGM 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	338/520 (65%)
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	338/520 (65%)