Protein Alignment Hsp60A and fab1

DIOPT Version :9

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 99/499 - (19%)
• Similarity: 167/499 - (33%)
• Gaps: 145/499 - (29%)

  Fly     3 RLPVSLARSSISRQLAMR----------GYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRN 57
            :|.|..:.||:::...|:          ||.:: ||.              :.....|:....|.
  Fly   270 KLEVQDSGSSLAKHPQMQRAPLPRKTSVGYQEE-RFS--------------SHPTYTTLSIDDRK 319

  Fly    58 VIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKE 122
            .|::||       ...:|:.:.::.....||.|.:|: :..|:.|:.|.:  ..|..:..|:...
  Fly   320 NILQQS-------NSLITLHEEMQRDLPAQNCGQRLI-EFLNSNNKSANE--VQAVAILNAMLAA 374

  Fly   123 GF-EKISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAM 186
            || |.|.  .:|.::.....|..:..|.:....||.:|...|               .|..:|..
  Fly   375 GFLEPIV--PDPEQMDFDSSLHYKFSKSSSSDTSRTMSPQFE---------------ANPHAEPQ 422

  Fly   187 KKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSK--GAKVEFQDALLLLSEKKISS 249
            .....|.....|: |.|.:|||      .||.|.:.    :||  .:..|.::.||
  Fly   423 PPKSMDQSAEEKE-KELENELE------NDRCYTTA----TSKLLASYCEHEEQLL--------- 467

  Fly   250 VQSIIPALELANAQRKPLVIIAEDIDGE------ALSTLVVNRLK----------IGLQVAAVKA 298
                        ||    ::.|.::|.|      .|.:...|..|          |...|...|.
  Fly   468 ------------AQ----MLRAHNLDQEWDKVLQMLCSTAANHFKPEHCSNDLMDIRNYVNFKKV 516

  Fly   299 PGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITK---DDTLLLKGKGKK 360
            || |..:.|.:......|..:...|.|..|....:.:.....|.|.:..|   .:|:||:.|...
  Fly   517 PG-GRRKDSKIVHGVAFSKNVAHKDMATHVPFPRILLLQCPIVYERIEGKFVTIETVLLQEKEYL 580

  Fly   361 DDVLRRANQIKDQI-----------EDTTSEYE-------KEKLQERLAR---------LASGVA 398
            .:|..|....|..:           :|....||       |..:.|||:|         :.|.:.
  Fly   581 RNVCARIMSFKPNVVLVHKNVAGIAQDLLRSYEVTLVLDVKLSVMERLSRTLQCDIVSSIESNIT 645

  Fly   399 LLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLR 442
            :.::|..::..:.....:       |....|:...|.|.|.|||
  Fly   646 MPKLGYCNDFYIRNYNGK-------TLMFFEKLTNPRGYTCLLR 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	96/490 (20%)
		GroEL	24..544	CDD:239460	92/468 (20%)
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489	16/72 (22%)
		Fab1_TCP	464..717	CDD:239450	49/252 (19%)
		PIPKc	1413..1797	CDD:295374

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930