Protein Alignment Hsp60A and CCT8

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_610418.1
• Gene: CCT8 / 35882
• FlyBaseID: FBgn0284436
• Length: 546
• Species: Drosophila melanogaster
• Alignment Length: 614
• Identity: 136/614 - (22%)
• Similarity: 239/614 - (38%)
• Gaps: 151/614 - (24%)

  Fly    23 AKDVRFGPEVRAMMLQGVDV---LADAV----------AVTM----GPKGRNVIIEQSWGSPKIT 70
            |..|...|.|..|:..|..:   |.:||          |.||    ||.|.|.:|........:|
  Fly     2 ALSVPKAPGVSQMLKDGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVT 66

  Fly    71 KDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVE 135
            .|..|:.:.:::    ::..|||:...:...:.|.||||....|||.|:.:...|.:..|....|
  Fly    67 SDAGTIMRELDV----EHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAE 127

  Fly   136 IRRGVMLAVETVKDNLKTM-------SRPVSTPEEIAQVATISANGDQA--IGNLISEAMKKVGR 191
            |..|...|:|...:.|..:       .|.|...:|:.:.:.:|....|.  :.:|:|:|...:..
  Fly   128 ISDGYEKALEKALEILPNLVSHKIEDYRNVEKVKEVLRTSIMSKQYGQEDFLNDLVSKACVSILP 192

  Fly   192 D-GVITVKD-------GKTLTDELEVIEGMKFDR---GYIS------------PYFI--NSSKG- 230
            | |...|.:       |..|| :.||:.||.|.|   |.::            |..|  ..:||
  Fly   193 DEGTFNVDNIRICKILGSGLT-KSEVVRGMVFKRFVEGDVTYAEKAKIVIFSCPVDIIQTETKGT 256

  Fly   231 AKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRL-KIGLQVA 294
            ..::..|.||..|..:.|.::|.|.|:..|..:    |::|    |..:..:.::.| |.||.
  Fly   257 VLIKSADELLSFSSGEESLLESQIKAIADAGVK----VVVA----GGKVGDMALHFLNKYGLM-- 311

  Fly   295 AVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGK 359
            ||:.....|.|:.:.:..|.....|......:|...:.|.:.:||          ||.::..:
  Fly   312 AVRLNSKFDLRRLSRSVNATVLPRITTPSQEELGYCDKVCIEELG----------DTTIVAFR-- 364

  Fly   360 KDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNAT 424
                    |:.||                      |.:|.:.:.|:::..:::.:..:.||:|..
  Fly   365 --------NEGKD----------------------SRIATVVIRGATDNFMDDIERALDDAINNF 399

  Fly   425 RAAVEEG-IVPGGG-------TALLRCIEKLEGVETTNEDQKLGVEIVRRALRMPCMTIAKNAGV 481
            :....:| .:||.|       |.|....:.|.|::      :..|.....||.:....:|:|:|:
  Fly   400 KCLTRDGRYLPGAGATEIELATQLSAYADTLPGLD------QYAVRKFANALEVFPKALAENSGI 458

  Fly   482 DGAMVVAKV----ENQAG-DYGYDALKGEYGNLIEKGIIDPTKVVRTAITD-----------ASG 530
            :|..:|.::    .|:|| ..|:| ::.|     :...||.||   ..:.|           |.|
  Fly   459 NGTEIVNQLYLAHNNEAGKTIGFD-IEAE-----KASTIDTTK---AKLFDLYQSKFWGLKYAVG 514

  Fly   531 VASLLTTAEAVVTEIPKEDGAPAMPGMGG 559
            .|:.:...:.::  :.|..|.|.:....|
  Fly   515 AAATILKVDQII--MAKRAGGPKVRQAAG 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	131/596 (22%)
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	126/582 (22%)