Protein Alignment Hsp60A and CCT4

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 121/560 - (21%)
• Similarity: 240/560 - (42%)
• Gaps: 86/560 - (15%)

  Fly    24 KDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQN 88
            ||.....:||...:|....::||:..::||:|.:.:|:...|...||.||.|:.|.:.:    .:
  Fly    18 KDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNV----LH 78

  Fly    89 IGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLKT 153
            ..||::.:::...:..||||||:..|:|.|:.:...:.:.||.:|..|............:.||.
  Fly    79 PAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQ 143

  Fly   154 MSRPVSTP--EEIAQVATISANG------DQAIGNLISEAMKKV---GRDGVITVKDGKTLT--- 204
            ||.|:...  |.:.:.|:.|.|.      ...:..:..:|:.||   |::..:.:|:.|.::
  Fly   144 MSTPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLG 208

  Fly   205 ---DELEVIEGMKF---DRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSII----PALE- 258
               ::.|:::|:.|   ..|..:|..|..:|...::|     .:|..|.....::|    .|::
  Fly   209 GTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQF-----CISAPKTDMDHNVIVSDYAAMDR 268

  Fly   259 LANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGD 323
            :...:|..::.|.:.|.....:.|:|                    :||.|.| |::.....|.|
  Fly   269 VLKEERSYILNIVKQIKKSGCNVLLV--------------------QKSILRD-AVSDLAQHFLD 312

  Fly   324 DADLVKLEDVKVSDLGQVGEVV----ITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKE 384
            ....:.::||:..|:..|.:.:    |...|....:.....|        :.:::...|:::.|.
  Fly   313 KIKCMVVKDVEREDIEFVCKTLHCRPIASLDHFTAENLSSAD--------LVEEVASGTNKFVKI 369

  Fly   385 KLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVE-EGIVPGGGTALLRCIEKLE 448
            ...:.:.|..|.:.    .||:::.:.|....:||||...|..|: ...:.|||...:....:|.
  Fly   370 TGIQNMGRTVSIIC----RGSNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLA 430

  Fly   449 GVETTNEDQKLGVE-----IVRRALRMPCMTIAKNAGVDGAMVVAKVENQAG----DYGYDALKG 504
            .:..|.|    ||:     ....||.:...|:|:|||::....|.::.|:..    :.|.:..||
  Fly   431 ALAQTVE----GVDAYCFRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKG 491

  Fly   505 EYGNLIEKGIIDPTKVVRTAITDAS-GVASLLTTAEAVVT 543
            ...::..:.::.|..|..::||.|: .:.|:|...:.|.|
  Fly   492 AITDIFAENVVQPLLVSISSITLATETIRSILKIDDIVNT 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	121/560 (22%)
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	120/558 (22%)